Lu Chen

ORCID: 0000-0003-3424-9480 · 20 papers in corpus
observational 2026
Frontiers in endocrinology ·doi:10.3389/fendo.2026.1822884

OBJECTIVE: To investigate the association between the dynamic trajectories of urinary human chorionic gonadotropin (hCG) and the risk of early miscarriage after embryo transfer. METHODS: In this prospective cohort study conducted in Hebei …

lab-animal 2026
Chinese medicine ·doi:10.1186/s13020-026-01451-8

BACKGROUND: Pro-EGCG has shown therapeutic promise for endometriosis, yet its immunoregulatory mechanisms remain unclear. Myeloid-derived suppressor cells (MDSCs) are key drivers of disease progression. This study investigates whether Pro-E…

review 2024
Frontiers in endocrinology ·doi:10.3389/fendo.2024.1456571

Polycystic ovary syndrome (PCOS) is the most prevalent endocrine disorder in women of reproductive age, and presents a significant challenge to the global population. This review provides comprehensive evidence of interventions, including f…

review 2024
Bioactive materials ·doi:10.1016/j.bioactmat.2023.11.021

Intervertebral disc degeneration (IVDD) is rising worldwide and leading to significant health issues and financial strain for patients. Traditional treatments for IVDD can alleviate pain but do not reverse disease progression, and surgical …

other 2024
BMC women's health ·doi:10.1186/s12905-024-03196-8

BACKGROUND: Observational data indicates a connection between emotional discomfort, such as anxiety and depression, and uterine fibroids (UFs). However, additional investigation is required to establish the causal relationship between them.…

other 2023
BMC cancer ·doi:10.1186/s12885-023-11108-6

BACKGROUND: Diffuse large B-cell lymphoma (DLBCL) is one of the most aggressive malignant tumors. Chromobox (CBX) family plays the role of oncogenes in various malignancies. METHODS: The transcriptional and protein levels of CBX family wer…

other 2023
Medical science monitor : international medical journal of experimental and clinical research ·doi:10.12659/msm.939314

BACKGROUND We aimed to investigate the clinical efficacy of continuous renal replacement therapy (CRRT) in combination with peritoneal lavage for the treatment of severe acute pancreatitis. MATERIAL AND METHODS We retrospectively reviewed d…

other 2023
Frontiers in pharmacology ·doi:10.3389/fphar.2023.1274946

[This corrects the article DOI: 10.3389/fphar.2023.1199010.].

other 2023
Frontiers in pharmacology ·doi:10.3389/fphar.2023.1254518

[This corrects the article DOI: 10.3389/fphar.2023.1199010.].

review 2023
Frontiers in pharmacology ·doi:10.3389/fphar.2023.1199010

Endometriosis is one of the most common benign gynecological disorders in reproductive-aged women. The major symptoms are chronic pelvic pain and infertility. Despite its profound impact on women's health and quality of life, its pathogenes…

review 2021
The Journal of international medical research ·doi:10.1177/03000605211033194

Disseminated peritoneal leiomyomatosis (DPL), also known as leiomyomatosis peritonealis disseminata, is a rare disease characterized by multiple benign smooth muscle tumors proliferating along the peritoneal surfaces. The cause of the disea…

review 2021
Stem cells international ·doi:10.1155/2021/8882368

Infertility is a global reproductive disorder which is caused by a variety of complex diseases. Infertility affects the individual, family, and community through physical, psychological, social and economic consequences. The results from re…

other 2021
BioMed research international ·doi:10.1155/2021/6464686

OBJECTIVE: To explore the mechanisms of follicular fluids (FFs) on granulose cell (GC) apoptosis in endometriosis-associated infertility. MATERIALS AND METHODS: 60 infertile women were enrolled. The FFs from 30 endometriosis-associated inf…

meta-analysis 2020
BMC pregnancy and childbirth ·doi:10.1186/s12884-020-03248-5

BACKGROUND: In recent years, there have been many reports on the pregnancy outcomes of fresh blastocyst transfer (BT) and frozen-thawed BT, but the conclusions are controversial and incomplete. To compare the pregnancy outcomes, maternal co…

other 2019
Journal of clinical laboratory analysis ·doi:10.1002/jcla.22994

BACKGROUND: Some of the non-criteria autoantibodies, especially non-conventional antiphospholipid (aPL) antibodies, were present with high prevalence in sporadic miscarriages and recurrent pregnant loss. However, whether these autoantibodie…

meta-analysis 2018
Journal of cancer research and therapeutics ·doi:10.4103/0973-1482.188439

PURPOSE: An association between catechol-O-methyltransferase (COMT) 158G/A polymorphism and endometriosis/adenomyosis susceptibility has been reported in the previous studies, but the results were inconsistent. This study was conducted to e…

review 2018
The Journal of endocrinology ·doi:10.1530/joe-17-0544

Retinol (vitamin A) and its derivatives, collectively known as retinoids, are required for maintaining vision, immunity, barrier function, reproduction, embryogenesis and cell proliferation and differentiation. Despite the fact that most ev…

observational 2011
Archives of gynecology and obstetrics ·doi:10.1007/s00404-010-1574-2

OBJECTIVE: To explore and compare the differences in the clinicopathological characteristics and prognosis of synchronous primary endometrial and ovarian cancers with primary endometrial cancer metastatic to adnexa. MATERIALS AND METHODS: …

nonrandomized-trial 2011
·doi:10.3760/cma.j.issn.1008-1372.2011.04.006

Objective To investigate the effect on the menstrual patterns and sexual quality of life of patients with adenomyosis after treated with Mirena IUD.Methods 56 patients with adenomyosis who were treated with Mirena IUD were recruited from Au…

diagnostic-accuracy 2008
The American Journal of Pathology ·doi:10.2353/ajpath.2008.080250

No adequate means exist to identify the minority of ulcerative colitis (UC) patients destined to undergo neoplastic progression. Recognition of this subset would advance UC cancer surveillance by focusing the available management options on…