Akiko Nakamura

ORCID: 0000-0001-7331-7621 · 15 papers in corpus
review 2026
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1007/s43032-026-02059-x

The pathogenesis and progression of endometriosis may involve a complex combination of multiple factors, including chronic inflammation and oxidative stress. Hormonal therapy, the current standard for pharmacotherapy in endometriosis, cause…

lab-animal 2025
Biochemistry and cell biology = Biochimie et biologie cellulaire ·doi:10.1139/bcb-2025-0014

The most common medical therapy for endometriosis suppresses ovulation, which is a barrier for patients planning pregnancy. To address this issue, we focused on the cell proliferation-suppressing effects of lactoferrin, which reportedly in …

review 2024
Molecular human reproduction ·doi:10.1093/molehr/gaae041

Mammalian target of rapamycin (mTOR) inhibitors have been used clinically as anticancer and immunosuppressive agents for over 20 years, demonstrating their safety after long-term administration. These inhibitors exhibit various effects, inc…

observational 2023

Endometriosis is a disease that is characterized by the ectopic presence of the endometrium or its similar cells. A high prevalence of patients with autoimmune diseases has been reported among patients with endometriosis although the cause …

observational 2023
The Tohoku Journal of Experimental Medicine ·doi:10.1620/tjem.2022.J106

Endometriosis is a disease that is characterized by the ectopic presence of the endometrium or its similar cells. A high prevalence of patients with autoimmune diseases has been reported among patients with endometriosis although the cause …

lab-animal 2023
Reproductive medicine and biology ·doi:10.1002/rmb2.12540

PURPOSE: This study aimed to explore whether umbilical cord-derived mesenchymal stem cells (UC-MSCs) could be used as a therapeutic resource for endometriosis. METHODS: Of seven cynomolgus monkeys with endometriosis, five were administered…

observational 2022

Chronic inflammation in cesarean scar defect contributes to secondary infertility in women with cesarean scar syndrom; however, it remains unclear about the situation of inflammation in uterine cavity in women with cesarean scar syndrome. T…

observational 2022
The Tohoku Journal of Experimental Medicine ·doi:10.1620/tjem.2022.j082

Chronic inflammation in cesarean scar defect contributes to secondary infertility in women with cesarean scar syndrom; however, it remains unclear about the situation of inflammation in uterine cavity in women with cesarean scar syndrome. T…

observational 2022
The Tohoku Journal of Experimental Medicine ·doi:10.1620/tjem.2022.j106

Endometriosis is a disease that is characterized by the ectopic presence of the endometrium or its similar cells. A high prevalence of patients with autoimmune diseases has been reported among patients with endometriosis although the cause …

2022
·doi:10.1016/b978-0-323-90805-4.00002-x
case-report 2021
Journal of Obstetrics and Gynaecology Research ·doi:10.1111/jog.14898

The formation of microbleed and minute tissue necrosis inside adenomyosis after the shedding of endometrial or endometrial-like tissue within the myometrium during menstruation is receiving attention as a new pathological condition of uteri…

observational 2021
BMC women's health ·doi:10.1186/s12905-021-01239-y

BACKGROUND: The diagnostic criteria of chronic endometritis remain controversial in the treatment for infertile patients. METHODS: A prospective observational study was conducted in a single university from June 2014 to September 2017. Pat…

observational 2021
Reproductive medicine and biology ·doi:10.1002/rmb2.12431

PURPOSE: To explore the histopathological findings of cesarean scar defect (CSD) and the immunological component in women with cesarean scar syndrome (CSS). METHODS: This retrospective study was conducted in a university hospital and a pub…

observational 2021
PloS one ·doi:10.1371/journal.pone.0249775

BACKGROUND: The purpose of the present study was to evaluate the relationship between chronic endometritis and the epithelial-mesenchymal transition in the endometrium of infertile patients in the implantation phase. METHODS: Endometrial b…

other 2020
BMC women's health ·doi:10.1186/s12905-020-00982-y

BACKGROUND: The presence of chronic deciduitis (CD) was determined in patients diagnosed with or without chronic endometritis (CE) before pregnancy. OBJECTIVE: To study the effect of CE on decidua in cases of miscarriage. METHODS: Decidua…