Angel Hsin-Yu Pai

PURPOSE: This case-control study investigated whether ovarian endometriosis is associated with altered estrogen metabolism and gut or urogenital microbiota by analyzing enzyme activity, bacterial composition, and variations of estrogen meta…

OBJECTIVE: To study the effect of adenomyosis on the localized expression of the GATA binding proteins 2 and 6 (GATA2 and GATA6) zinc-finger transcription factors that are involved in proliferation of hematopoietic and endocrine cell lineag…

INTRODUCTION Within the myometrium, the ectopic endometrial tissues, which often migrate from the basalis layer and clonally expand,[1] express diffuse epigenic defects that result in altered responses of estrogens, resistances to progester…

Adenomyosis, endometriosis of the uterus, is associated with an increased likelihood of abnormal endometrial molecular expressions thought to impair implantation and early embryo development, resulting in disrupted fertility, including the …

Microbiota is associated with our bodily functions and microenvironment. A healthy, balanced gut microbiome not only helps maintain mucosal integrity, prevents translocation of bacterial content, and contributes to immune status, but also a…

A 31-year-old, nulligravid female with painful menorrhagia received a sonographic examination that displayed a 3.3 cm × 2.7 cm solid mass on her uterus [Figure 1]. Subsequent laparoscopic surgery revealed a well-circumscribed mass, which re…