Tatjana Gibbons

INTRODUCTION: Global total fertility rates (TFR) are declining by approximately 1% annually due to factors such as increasing use of contraceptives, urbanisation, a shift in social norms, educational and socioeconomic changes among others. …

Background Novel non-invasive or minimally invasive diagnostic tests for endometriosis are a research priority. Superficial peritoneal endometriosis, the most prevalent subtype of endometriosis (80% of all laparoscopically diagnosed disease…

RATIONALE: Endometriosis is defined as the presence of endometrium-like tissue developing outside the uterine cavity. This condition is oestrogen-dependent and thus is seen primarily during the reproductive years. Owing to their antiprolife…

Guidance on standards of care, particularly incorporating region-specific needs, is foundational to high-quality healthcare. The availability of region-specific guidance on endometriosis care has not been documented, especially in low- and …

Endometriosis is an inflammatory condition affecting approximately 10% of the female-born population. Despite its prevalence, the lack of noninvasive biomarkers has contributed to an established global diagnostic delay. The intricate pathop…

BACKGROUND: 99m Tc-Maraciclatide is a radiolabelled RGD (Arg-Gly-Asp) peptide that binds with high affinity to α v β 3 and α v β 5 integrins, common receptors upregulated in disease states involving angiogenesis and inflammation. As such, i…

Background and Aims: Numerous endometriosis treatments exist, ranging from surgical to traditional medications to complementary and alternative medicines (CAMs). The ranking of treatments across management categories remains unknown. To add…

BACKGROUND: Many factors influence fertility, one being the timing of intercourse. The 'fertile window' describes a stage in the cycle when conception can occur and is approximately five days before to several hours after ovulation. 'Timed …

Scoping review assessing the current literature regarding the role of integrins in endometriosis.

BACKGROUND: Endometriosis is a condition characterised by the presence of ectopic deposits of endometrial-like tissue outside the uterus, usually in the pelvis. The impact of laparoscopic treatment on overall pain is uncertain and a signifi…

Abstract Study question Does levonorgestrel-releasing intrauterine device (LNG-IUD) improve post-operative outcomes for endometriosis when compared to other systemic hormonal treatments or no additional treatment? Summary answer We are unce…

BACKGROUND: Chronic pelvic pain (CPP) is a common gynaecological condition accounting for 20% of all gynaecological referrals. There are wide ranges of causes with overlapping symptomatology, therefore the management of the condition is a f…

(Abstracted from J Minim Invasive Gynecol 2020;27:390–407) Endometriosis is an inflammatory disease characterized by endometrium-like lesions outside the uterus. Pelvic pain and infertility are hallmarks of the disorder.

OBJECTIVE: We performed a systematic review and meta-analysis with the aim to answer whether operative laparoscopy is an effective treatment in a woman with demonstrated endometriosis compared with alternative treatments. Moreover, we aimed…