Dou X

ORCID: 0009-0001-6929-1585 · 3 papers in corpus
lab-animal 2026
Single-cell atlas of the developing mouse oviduct reveals smooth muscle heterogeneity and identifies Vps34 as a critical regulator of female fertility.
BMC biology ·doi:10.1186/s12915-026-02706-4

BackgroundThe oviduct smooth muscle layer is traditionally regarded as a contractile unit. Limited understanding exists regarding the molecular heterogeneity and intercellular communication during development timeline, which is critical for…

lab-animal 2022
Blockade of prostaglandin E2 receptor 4 ameliorates peritoneal dialysis-associated peritoneal fibrosis
Frontiers in pharmacology ·doi:10.3389/fphar.2022.1004619

Inflammatory responses in the peritoneum contribute to peritoneal dialysis (PD)-associated peritoneal fibrosis. Results of our previous study showed that increased microsomal prostaglandin E synthase-1-mediated production of prostaglandin E…

lab-animal 2021
Enhanced mPGES-1 Contributes to PD-Related Peritoneal Fibrosis via Activation of the NLRP3 Inflammasome
Frontiers in medicine ·doi:10.3389/fmed.2021.675363

Background: Microsomal prostaglandin E synthase-1 (mPGES-1)-derived prostaglandin E2 (PGE2) is a chief mediator of inflammation. However, the role and mechanism of mPGES-1 in peritoneal dialysis (PD)-associated peritoneal fibrosis have not …