Yi Feng

ORCID: 0000-0002-7156-6023 · 12 papers in corpus
other 2025
NPJ precision oncology ·doi:10.1038/s41698-025-00849-1

Long interspersed element 1 (LINE-1) retrotransposons are repetitive sequences that can move within the genome by an autonomous mechanism. To limit their mutagenic potential, benign cells restrict LINE-1 expression through molecular mechani…

other 2024
Discover oncology ·doi:10.1007/s12672-024-01175-x

Cancer-associated fibroblasts (CAFs), integral components of the tumor microenvironment, play a pivotal role in tumor proliferation, metastasis, and clinical outcomes. However, its specific roles in Kidney Renal Clear Cell Carcinoma (KIRC) …

review 2022
Human Reproduction ·doi:10.1093/humrep/deac156

During human evolution, major changes in our societal conditions and environment took place without sufficient time for concomitant genetic alterations, leading to out of step adaptation and diseases in women. We first discuss recent societ…

observational 2017
Journal of ovarian research ·doi:10.1186/s13048-016-0298-8

BACKGROUND: MicroRNAs (miRNAs) regulate the expression of genes involved in various cellular functions related to metabolism, inflammation, and reproduction. This study evaluated the effects of sex hormones and obesity on the expression of …

other 2016
Data in brief ·doi:10.1016/j.dib.2015.11.048

In this data, non-pregnant women during the menstrual cycle, women with normal intrauterine pregnancy (IUP), and women with tubal ectopic pregnancy (EP) after informed consent were included. The serum levels of 17β-estradiol, progesterone, …

meta-analysis 2015
Reproductive BioMedicine Online ·doi:10.1016/j.rbmo.2015.05.017

Endometriosis is a chronic, inflammatory and common gynaecological disease. This study investigated the association between TP53 codon 72 polymorphism and the risk of endometriosis. A search for relevant articles was conducted in PubMed, Em…

review 2014
Journal of Biomedical Science ·doi:10.1186/1423-0127-21-2

Polycystic ovary syndrome (PCOS) is a state of altered steroid hormone production and activity. Chronic estrogen exposure or lack of progesterone due to ovarian dysfunction can result in endometrial hyperplasia and carcinoma. A key contribu…

review 2014
American journal of translational research

Endometriosis is a complex and challenging disease that involves aberrant adhesion, growth, and progression of endometrial tissues outside of the uterine cavity, and there is evidence to suggest that estrogen plays a key role in its develop…

other 2014
International journal of clinical and experimental pathology

Human ectopic pregnancy (EP) is a leading cause of pregnancy-related death, but the molecular basis underlying the onset of tubal EP is largely unknown. Female Dicer1 conditional knockout mice are infertile with dysfunctional Fallopian tube…

diagnostic-accuracy 2013
Journal of translational medicine ·doi:10.1186/1479-5876-11-44

BACKGROUND: Several peripheral proteins that might be useful for detecting the presence of ectopic pregnancy (EP) have been evaluated, but none have been proven entirely useful in the clinic. We investigated the presence and the possible ch…

review 2012
American journal of translational research

17β-estradiol, acting through estrogen receptors α and β, plays a fundamental role in the regulation of Fallopian tube cell homeostasis and in the modulation of normal tubal physiological processes. Fluctuations in E2 levels also play cruci…

other 2011
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jc.2010-2353

CONTEXT: Tissue-specific dicer1 knockout mice display severe, irreversible Fallopian tube damage and disrupted tubal transport. It is not known how Dicer1 affects human Fallopian tube function. OBJECTIVE: The aim of the study was to invest…