Giannoulis Fakis

ORCID: 0000-0003-1613-3943 · 3 papers in corpus
review 2008
Current trends in N-acetyltransferase research arising from the 2007 International NAT Workshop
Pharmacogenomics ·doi:10.2217/14622416.9.6.765

Arylamine N-acetyltransferase (NAT) research has been influenced in recent years by the rapid progress in genomics, proteomics, structural genomics and other cutting-edge disciplines. To keep up with these advancements, the NAT scientific c…

lab-animal 2007
Description of a novel polymorphic gene encoding for arylamine N-acetyltransferase in the rhesus macaque (Macaca mulatta), a model animal for endometriosis
Pharmacogenetics and genomics ·doi:10.1097/FPC.0b013e328011e3ad

OBJECTIVES: Case-control studies have previously associated polymorphisms in the gene encoding the xenobiotic metabolizing enzyme arylamine N-acetyltransferase 2 (NAT2) with endometriosis, a common multifactorial disease in women. These stu…

other 2005
Allelic loss studies do not provide evidence for the "endometriosis-as-tumor" theory
Fertility and sterility ·doi:10.1016/j.fertnstert.2004.07.982

OBJECTIVE: To identify consistent genetic changes in endometriosis samples to determine whether endometriosis lesions are true neoplasms. DESIGN: We analyzed ovarian endometriosis lesions for loss of heterozygosity (LOH) at 12 loci of pote…