Kartik Shankar

ORCID: 0000-0002-7964-9026 · 3 papers in corpus
observational 2019
Obesity leads to distinct metabolomic signatures in follicular fluid of women undergoing in vitro fertilization
American journal of physiology. Endocrinology and metabolism ·doi:10.1152/ajpendo.00401.2018

Although obesity negatively influences the metabolic homeostasis of cells within a broad range of tissues, its impact on oocyte metabolism is not fully understood. Prior evidence suggests that obesity increases expression of oocyte genes as…

observational 2017
Obesity Modulates Inflammation and Lipid Metabolism Oocyte Gene Expression: A Single-Cell Transcriptome Perspective
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jc.2016-3524

CONTEXT: It is hypothesized that obesity adversely affects the ovarian environment, which can disrupt oocyte maturation and embryonic development. OBJECTIVE: This study aimed to compare oocyte gene expression profiles and follicular fluid …

lab-animal 2012
Krüppel-like factor 9 and progesterone receptor coregulation of decidualizing endometrial stromal cells: implications for the pathogenesis of endometriosis
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jc.2011-2562

CONTEXT: Endometriosis is characterized by progesterone resistance and associated with infertility. Krüppel-like factor 9 (KLF9) is a progesterone receptor (PGR)-interacting protein, and mice null for Klf9 are subfertile. Whether loss of KL…