Ellen Menkhorst

ORCID: 0000-0003-2440-6665 · 9 papers in corpus
lab-animal 2024
Proceedings of the National Academy of Sciences of the United States of America ·doi:10.1073/pnas.2401071121

The endometrium undergoes substantial remodeling in each menstrual cycle to become receptive to an implanting embryo. Abnormal endometrial receptivity is one of the major causes of embryo implantation failure and infertility. MicroRNA-124-3…

review 2023
Molecular human reproduction ·doi:10.1093/molehr/gaad012

This review leads the 2023 Call for Papers in MHR: 'Cyclical function of the female reproductive tract' and will outline the complex and fascinating changes that take place in the reproductive tract during the menstrual cycle. We will also …

lab-animal 2021
Frontiers in cell and developmental biology ·doi:10.3389/fcell.2021.647496

Poor pregnancy outcomes such as recurrent pregnancy loss (RPL) and preeclampsia are associated with impaired decidualization and abnormal trophoblast invasion. Emerging evidence suggests that use of corticosteroids, including prednisolone a…

lab-animal 2019
Oncology letters ·doi:10.3892/ol.2019.10588

Endometrial cancer is the most common gynaecological cancer worldwide, and the prognosis of patients with advanced disease remains poor. MicroRNAs (miRs) are dysregulated in endometrial cancer. miRs-29-a, -b and -c expression levels are dow…

lab-animal 2018
Oncology letters ·doi:10.3892/ol.2018.9193

Endometrial cancer (EC) is the most commonly diagnosed gynecological malignancy in Australian women. Notably, its incidence and mortality rate is increasing. Despite this, there are limited treatment options for EC. Galectin-7 regulates tum…

review 2016
Nature reviews. Endocrinology ·doi:10.1038/nrendo.2016.116

The human endometrium is a highly dynamic tissue that is cyclically shed, repaired, regenerated and remodelled, primarily under the orchestration of oestrogen and progesterone, in preparation for embryo implantation. Humans are among the ve…

other 2014
Molecular human reproduction ·doi:10.1093/molehr/gau032

Menstruation involves the shedding of the functional layer of the endometrium in the absence of pregnancy. At sites where tissue shedding is complete, re-epithelialization of the tissue is essential for repair and termination of bleeding. T…

lab-animal 2011
PloS one ·doi:10.1371/journal.pone.0019665

Female-controlled contraception/HIV prevention is critical to address health issues associated with gender inequality. Therefore, a contraceptive which can be administered in tandem with a microbicide to inhibit sexually transmitted infecti…

lab-animal 2009
Biology of reproduction ·doi:10.1095/biolreprod.108.073601

Hormonal contraceptives are unsuitable for many women; thus, the development of new, nonhormonal contraceptives is of great interest. In women, uterine epithelial expression of interleukin 11 (IL11) and its receptor (IL11RA) suggests IL11 i…