Chronic endometritis (CE) is a plasma cell-related endometrial inflammatory phenotype that may compromise fertility, while endometriosis (EM) is an immune-mediated inflammatory disorder. However, whether EM is associated with CD138-defined …
BACKGROUND: Laparoscopic ethanol sclerotherapy is a fertility-preserving alternative for ovarian endometriomas, but the appropriate ethanol exposure duration remains uncertain. We compared expectant management with 5- and 15-minute ethanol …
STUDY OBJECTIVE: To compare the safety and efficacy of laparoscopic versus transvaginal ethanol sclerotherapy in patients with ovarian endometriomas (OEMs). DESIGN: Preliminary retrospective cohort study. SETTING: Reproductive Medicine Re…
STUDY OBJECTIVE: To evaluate the effects of a 3-stage treatment strategy featured by cold-knife adenomyomectomy, enhanced endometrial protection and postoperative uterine monitoring for severe diffuse adenomyosis on IVF/ICSI and perinatal o…
PURPOSE: To compare the effects of the gonadotrophin-releasing hormone (GnRH) agonist protocol, GnRH antagonist protocol, progestin-primed ovarian stimulation (PPOS) protocol, and mild stimulation/natural cycle protocol on the cumulative li…
BACKGROUND: Polycystic ovary syndrome (PCOS) is known to be associated with chronic low-grade inflammation and endometrial dysfunction. Chronic endometritis (CE) is a type of local inflammation that can contribute to endometrial dysfunction…
To explore the expression profiles of mRNAs, long-noncoding RNAs (lncRNAs), circular RNAs (circRNAs) and construct the competitive endogenous RNA networks in granulosa cells (GCs) of infertile women with ovarian endometriosis. RNA sequencin…
BACKGROUND: Endometriosis negatively affects fertility, and it is a common disease in assisted reproductive practice. Surgical removal of endometriotic lesions is widely carried out to relieve symptoms and promote fertility. But it is not i…
BACKGROUND: Adenomyosis affects the outcomes of spontaneous fertility and assisted reproductive technology. The single blastocyst embryo transfer (SBT) policy is an effective strategy known to minimize the risk of multiple pregnancy for non…
It has been previously reported that the long non-coding RNA nuclear enriched abundant transcript 1 (NEAT1) can regulate cell apoptosis. The present study aimed to investigate the involvement of NEAT1 in premature ovarian failure (POF). A t…
The alteration of PTEN expression may be a vital part of the pathological and physiological mechanisms in infertility-related with endometriosis. However, the potential mechanisms underlying abnormal expression of PTEN and its role in proge…