Clyde MA

ORCID: 0000-0002-3595-1872 · 3 papers in corpus
other 2016
Risk Prediction for Epithelial Ovarian Cancer in 11 United States-Based Case-Control Studies: Incorporation of Epidemiologic Risk Factors and 17 Confirmed Genetic Loci
American Journal of Epidemiology ·doi:10.1093/aje/kww091

Previously developed models for predicting absolute risk of invasive epithelial ovarian cancer have included a limited number of risk factors and have had low discriminatory power (area under the receiver operating characteristic curve (AUC…

observational 2010
Association between DNA damage response and repair genes and risk of invasive serous ovarian cancer
PloS one ·doi:10.1371/journal.pone.0010061

BACKGROUND: We analyzed the association between 53 genes related to DNA repair and p53-mediated damage response and serous ovarian cancer risk using case-control data from the North Carolina Ovarian Cancer Study (NCOCS), a population-based,…

observational 2008
Polymorphism in the IL18 gene and epithelial ovarian cancer in non-Hispanic white women
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology ·doi:10.1158/1055-9965.epi-08-0548

Over 22,000 cases of ovarian cancer were diagnosed in 2007 in the United States, but only a fraction of them can be attributed to mutations in highly penetrant genes such as BRCA1. To determine whether low-penetrance genetic variants contri…