Xiaofei Chen

ORCID: 0000-0002-6252-5879 · 2 papers in corpus

lab-animal 2023

Drug repurposing based on the similarity gene expression signatures to explore for potential indications of quercetin: a case study of multiple sclerosis

Frontiers in chemistry ·doi:10.3389/fchem.2023.1250043

Quercetin (QR) is a natural flavonol compound widely distributed in the plant kingdom with extensive pharmacological effects. To find the potential clinical indications of QR, 156 differentially expressed genes (DEGs) regulated by QR were o…

other 2018

The Clinical and Experimental Research on the Treatment of Endometriosis with Thiostrepton

Anti-cancer agents in medicinal chemistry ·doi:10.2174/1871520618666180108100211

BACKGROUND/OBJECTIVE: Forkhead Box M1 (FOXM1) is frequently activated in tumors. We studied the expression and the possible mechanism of FOXM1 and evaluated the effects of thiostrepton in an endometriotic rat model. METHODS AND MATERIAL: T…