Carolyn Jones

This depository contains all microscopy images presented in ‘Menstrual flow as a non-invasive source of endometrial organoids’ paper accepted at Communications Biology; Tereza Cindrova-Davies et al. present a method for deriving endometrial…

Assessment of the endometrium often necessitates a biopsy, which currently involves an invasive, transcervical procedure. Here, we present an alternative technique based on deriving organoids from menstrual flow. We demonstrate that organoi…

In order for embryo implantation to occur, there must be synchronisation between the development of the blastocyst and the differentiating endometrium, which is refractory to implantation for all but about four days of the menstrual cycle. …

OBJECTIVES: To test the hypothesise that the treatment protocol used for preparation of the endometrium for frozen embryo transfer (ET) has a beneficial effect on the disorganised endometrium in women with endometriosis and leads to a highe…

BACKGROUND: Endometriosis is a common cause of infertility and pelvic pain. Lectin histochemistry has shown that glycan expression is a sensitive marker of differentiation in the normal endometrium. Endometrial biopsies were taken during th…

Experimentally induced endometriosis in baboons serves as an elegant model to discriminate between endometrial genes which are primarily associated with normal endometrial function and those that are changed by the presence of endometriotic…

Endometrial curettings from a cohort of 24 women with endometriosis were compared with matched biopsies from 14 healthy, fertile women and examined for ultrastructural changes and the secretion of glycans bound by the lectin from Dolichos b…

Examination of 12 paired peritoneal ectopic and eutopic endometria for histochemical binding of Dolichos biflorus agglutinin, normally found in the mid-late secretory part of the cycle, showed a failure of lectin binding in 9 of 11 secretor…

Following a study in a baboon model of endometriosis, we here describe the morphology of ectopic peritoneal lesions in the human to examine the effects of an ectopic site on glandular structure and function. Ectopic biopsies from 17 women w…

BACKGROUND: Endometriosis is one of the most common causes of infertility and pelvic pain. A baboon model has recently been developed whereby the intrapelvic injection of menstrual endometrium results in the induction of endometriotic lesio…

Conference Article| November 01 1997 Progesterone regulates glycosylation in endometrium J. D. Aplin; J. D. Aplin 1 *Department of Obstetrics and Gynaecology, University of Manchester, St Mary's Hospital, Manchester M13 0JH, U.K. 1To whom c…