Introduction: Endometriosis, defined as the growth of endometrial tissue outside \nthe uterine cavity is a common gynaecological disorder affecting 10-15% \nof women in their reproductive years. It is a major clinical problem causing in- \n…
Patients and Methods: Endometrial tissues were collected from women with regular menstrual cycles; tissues were used for recovery of primary ESC or RNA extraction or were fixed for immunohistochemistry. Primary ESC were decidualized in vitr…
OBJECTIVE: To examine whether thin endometria can be improved by increasing uterine radial artery (uRA) blood flow. DESIGN: A prospective observational study. SETTING: University hospital and city general hospital. PATIENT(S): Sixty-one …
BACKGROUND: Blood flow in the corpus luteum (CL) is associated with luteal function. The present study was undertaken to investigate whether luteal function can be improved by increasing CL blood flow in women with luteal phase defect (LFD)…
OBJECTIVE: To summarize the role of melatonin in the physiology and pathophysiology of the ovary. DESIGN: Review of literature. SETTING: University Health Science Center. RESULT(S): Melatonin plays an essential role in the pathogenesis o…
OBJECTIVE: To characterize pathophysiologic features of a "thin" endometrium. DESIGN: A prospective observational study. SETTING: University Hospital and City General Hospital. PATIENT(S): Patients with normal-thickness endometrium (Norm…
Immunohistochemistry for vascular endothelial growth factor (VEGF) and its receptors, fms-like tyrosine kinase (flt-1) and kinase insert domain-containing region (KDR), was performed on human endometrium obtained from patients with normal m…
The present study was undertaken to investigate the effect of decidualization on superoxide dismutase (SOD) expression in human endometrial stromal cells (ESC). To induce decidualization, isolated ESC were incubated with medroxyprogesterone…
This study investigated the involvement of lipid peroxidation and antioxidant enzymes in the regulation of luteal function in pseudopregnant rats. The activities of superoxide dismutase (SOD), a specific scavenger of superoxide radicals, an…