Wen Li

ORCID: 0000-0001-9468-5570 · 11 papers in corpus
other 2026
Scientific reports ·doi:10.1038/s41598-026-51553-4

Ovarian cancer poses a significant clinical challenge due to its asymptomatic onset and poor prognosis, highlighting the critical need for effective early detection strategies. This study developed a framework that integrates serum proteomi…

lab-animal 2026
BMC medicine ·doi:10.1186/s12916-026-04757-4

BACKGROUND: The ovary is a vital and dynamic reproductive organ. Ovarian tissue cryopreservation (OTC) plays a vital role in preserving female fertility. However, the cellular subtypes most susceptible to cryoinjury and the molecular mechan…

other 2026
BMC women's health ·doi:10.1186/s12905-026-04431-0

BACKGROUND: Ovarian endometriosis(OEM) is a highly prevalent condition that significantly affects women’s health. Tissue-derived extracellular vesicles(Ti-EVs) contain multiple molecules that maintain intercellular communication. They parti…

observational 2025
Human reproduction open ·doi:10.1093/hropen/hoaf044

STUDY QUESTION: Do novel per- and poly-fluoroalkyl substances (Novel PFAS) have associations with premature ovarian insufficiency (POI)? SUMMARY ANSWER: Hexafluoropropylene oxide dimer acid (HFPO-DA), perfluorobutanoic acid (PFBA), perfluo…

observational 2025
Medicine ·doi:10.1097/md.0000000000044941

The Levonorgestrel-releasing Intrauterine System (LNG-IUS) is extensively utilized in the treatment of adenomyosis. However, the displacement and expulsion of the LNG-IUS bring significant challenges. This was a retrospective analysis compa…

other 2024
Trials ·doi:10.1186/s13063-023-07877-x

BACKGROUND: Polycystic ovary syndrome (PCOS), an incidence of 10-15% in women of reproductive age, shows sex hormone disorders, luteal insufficiency, and the tendency of placental villus space thrombus. The incidence of early pregnancy loss…

rct 2024
Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-024-01222-w

STUDY OBJECTIVE: To evaluate the efficacy and pregnancy outcomes of intrauterine balloon and intrauterine contraceptive devices in the prevention of adhesion reformation following hysteroscopic adhesiolysis in infertile women with moderate …

review 2024
Frontiers in physiology ·doi:10.3389/fphys.2024.1330702

Fetal membrane providing mechanical support and immune protection for the growing fetus until it ruptures during parturition. The abnormalities of fetal membrane (thickening, separation, etc.) are related to adverse perinatal outcomes such …

observational 2024
Reproductive medicine and biology ·doi:10.1002/rmb2.12596

PURPOSE: To explore whether spermatozoa from AZFc microdeletion patients affect their outcomes of intracytoplasmic sperm injection (ICSI). METHODS: Eighty-five patients with AZFc microdeletion were recruited. A control group of one hundred…

2023
·doi:10.53388/dct20230008
other 2022
Trials ·doi:10.1186/s13063-022-06428-0

BACKGROUND: Endometrial fibrosis caused by intrauterine adhesion (IUA) can lead to hypomenorrhea, amenorrhea, and even infertility and abortion. The postoperative recurrence rate of severe IUA remains high, giving rise to low pregnancy rate…