STUDY QUESTION: To what extent is male physical activity (PA) associated with fecundability (per-cycle probability of conception)? SUMMARY ANSWER: Preconception levels of vigorous, moderate, or total PA were not consistently associated wit…
BACKGROUND: The use of fertility indicators to predict ovulation has largely been studied for contraceptive purposes, while less so as fertility-promoting tools. OBJECTIVE: To investigate the association between fertility indicators and fe…
PURPOSE: To evaluate the relationships among history of asthma, asthma severity, and spontaneous abortion (SAB). METHODS: Pregnancy Study Online is a preconception cohort study of North American couples. During the preconception period, fe…
BACKGROUND: Migraine is common among females of reproductive age (estimated prevalence:17-24%) and may be associated with reproductive health through underlying central nervous system excitability, autoimmune conditions, and autonomic dysfu…
STUDY QUESTION: To what extent is female preconception antibiotic use associated with fecundability? SUMMARY ANSWER: Preconception antibiotic use overall was not appreciably associated with fecundability. WHAT IS KNOWN ALREADY: Antibiotic…
STUDY QUESTION: Do daughters of older mothers have lower fecundability? SUMMARY ANSWER: In this cohort study of North American pregnancy planners, there was virtually no association between maternal age ≥35 years and daughters' fecundabili…
PURPOSE: Asthma has been positively associated with irregular menses and infertility in some studies, but data are limited on the relation between asthma medication use and fecundability (i.e., average per-cycle probability of conception am…
OBJECTIVE: To evaluate the association between pregravid use of a variety of contraceptive methods and subsequent fecundability. DESIGN: Prospective cohort study. SETTING: Denmark and North America, 2007-19. PARTICIPANTS: 17 954 women wh…
The association between dietary fat and fertility is not well studied. We evaluated intakes of total fat, saturated fatty acids, monounsaturated fatty acids, polyunsaturated fatty acids, trans fatty acids (TFA), ω-3 fatty acids, and ω-6 fat…
BACKGROUND: Animal studies have shown that a high intake of galactose, a breakdown product of lactose, increases ovarian toxicity. Few epidemiologic studies, to our knowledge, have examined the association between dairy intake and fertility…
STUDY QUESTION: To what extent is preconception use of pain-relieving medication associated with female fecundability? SUMMARY ANSWER: Women who used naproxen or opioids had slightly lower fecundability than women who did not use any pain-…
PURPOSE: The aim of this study was to evaluate the association between menstrual cycle characteristics in early life and adulthood and fecundability. METHODS: Pregnancy Study Online (PRESTO) is an Internet-based preconception cohort study …