Alexis Laux‐Biehlmann

ORCID: 0000-0003-0508-3047 · 10 papers in corpus
lab-animal 2023
Frontiers in behavioral neuroscience ·doi:10.3389/fnbeh.2023.1118598

Endometriosis is a chronic, hormone-dependent, inflammatory disease, characterized by the presence and growth of endometrial tissue outside the uterine cavity. It is associated with moderate to severe pelvic and abdominal pain symptoms, sub…

lab-animal 2021
Scientific reports ·doi:10.1038/s41598-021-99177-0

ATP-dependent P2X3 receptors play a crucial role in the sensitization of nerve fibers and pathological pain pathways. They are also involved in pathways triggering cough and may contribute to the pathophysiology of endometriosis and overact…

other 2021
Science translational medicine ·doi:10.1126/scitranslmed.abd6469

Endometriosis is a common chronic inflammatory condition causing pelvic pain and infertility in women, with limited treatment options and 50% heritability. We leveraged genetic analyses in two species with spontaneous endometriosis, humans …

review 2021
Pain ·doi:10.1097/j.pain.0000000000002248

Endometriosis (ENDO) and interstitial cystitis/bladder pain syndrome (IC/BPS) are chronic pain conditions for which better treatments are urgently needed. Development of new therapies with proven clinical benefit has been slow. We have cond…

lab-animal 2020
Scientific reports ·doi:10.1038/s41598-020-58362-3

Endometriosis is a common gynaecological disease of women in reproductive age, and is thought to arise from retrograde menstruation and implantation of endometrial tissue, mostly into the peritoneal cavity. The condition is characterized by…

other 2020
Scientific reports ·doi:10.1038/s41598-020-62492-z

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

2019
lab-animal 2015
European journal of pain (London, England) ·doi:10.1002/ejp.800

BACKGROUND: Chronic pelvic pain (CPP) is a high burden for patients and society. It affects 15-24% of women in reproductive age and is an area of high unmet medical need. CPP can be caused by a wide range of visceral diseases such as abdomi…

review 2015
Trends in pharmacological sciences ·doi:10.1016/j.tips.2015.03.004

Endometriosis is a chronic, hormone-dependent, inflammatory disease, characterized by the presence and growth of endometrial tissue outside the uterine cavity. It affects 5-10% of the female population of reproductive age and is frequently …

lab-animal 2014
Journal of neuroscience methods ·doi:10.1016/j.jneumeth.2014.05.017

BACKGROUND: Chronic pelvic pain (CPP) is defined as long-lasting and severe pelvic pain persisting over six months in cyclic or non-cyclic chronic manner. Various pathologic conditions like endometriosis, abdominal infections, intra-periton…