Alexander Freis

ORCID: 0000-0002-8223-5166 · 6 papers in corpus
observational 2026
Archives of gynecology and obstetrics ·doi:10.1007/s00404-026-08335-0

PURPOSE: To characterise the effect of polycystic ovary syndrome (PCOS) on embryo morphokinetics via time-lapse imaging, including absolute time points, relative time intervals, and ratios representing cleavage synchronicity. METHODS: This…

other 2021
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1007/s43032-020-00362-9

In order to improve ART outcome, non-invasive embryo assessment is gaining more and more attention. Therefore, the aim of this study is to determine the consecutive implantation potential via the secretome between blastocysts with or withou…

2020
·doi:10.1055/s-0040-1717678

Zielsetzung 10-15 % aller Frauen im reproduktiven Alter sind von Endometriose betroffen. Dennoch sind die molekularen Mechanismen sowie die Pathogenese nicht vollständig geklärt. Das Ziel der Studie war, die unterschiedlichen Stadien der Er…

other 2020
Journal of assisted reproduction and genetics ·doi:10.1007/s10815-020-01905-4

PURPOSE: Endometriosis (EM) is a common gynecological disease affecting 10-15% of women of reproductive age. However, molecular mechanisms and pathogenesis are still not completely understood. Furthermore, due to the absence of a reliable c…

observational 2020
Frontiers in endocrinology ·doi:10.3389/fendo.2020.00246

Background: The impact of controlled ovarian stimulation (COS) during medically assisted reproduction (MAR) on human embryogenesis is still unclear. Therefore, we investigated if early embryonic development is affected by the type of gonado…

observational 2017
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719117741373

INTRODUCTION: Time-lapse technology allows almost continuous noninvasive assessment of embryonic development. It was shown previously that relative kinetics defining cleavage synchronicity are better predictors of blastocyst quality than ab…