Eszter Hegyi

No ORCID on file · 3 papers in corpus
other 2024
Carboxyl ester lipase hybrid 1 (CEL-HYB1) haplotypes confer varying risk for chronic pancreatitis
Scientific reports ·doi:10.1038/s41598-024-82077-4

The CEL-HYB1 hybrid allele of the carboxyl ester lipase (CEL) gene and its pseudogene (CELP) has been associated with chronic pancreatitis (CP). Recent work indicated that amino acid positions 488 and 548 in CEL-HYB1 determined pathogenicit…

meta-analysis 2023
Risk of chronic pancreatitis in carriers of the c.180C>T (p.Gly60=) CTRC variant: case-control studies and meta-analysis
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] ·doi:10.1016/j.pan.2023.05.013

Chymotrypsin C (CTRC) is a digestive serine protease produced by the pancreas that regulates intrapancreatic trypsin activity and provides a defensive mechanism against chronic pancreatitis (CP). CTRC exerts its protective effect by promoti…

other 2021
Common calcium-sensing receptor (CASR) gene variants do not modify risk for chronic pancreatitis in a Hungarian cohort
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] ·doi:10.1016/j.pan.2021.08.012

The calcium-sensing receptor (CASR) is expressed in the pancreas where it might regulate calcium concentrations in pancreatic secretions. Two independent studies reported conflicting results claiming that commonly occurring missense variant…