Juanjuan Wu

ORCID: 0000-0001-8210-1371 · 5 papers in corpus
lab-animal 2015
A role for retinoids in human oocyte fertilization: regulation of connexin 43 by retinoic acid in cumulus granulosa cells
Molecular human reproduction ·doi:10.1093/molehr/gav017

Retinoids are essential for ovarian steroid production and oocyte maturation in mammals. Oocyte competency is known to positively correlate with efficient gap junction intercellular communication (GJIC) among granulosa cells in the cumulus-…

lab-animal 2014
Estrogen increases Nrf2 activity through activation of the PI3K pathway in MCF-7 breast cancer cells
Experimental cell research ·doi:10.1016/j.yexcr.2014.08.030

The actions of the transcription factor Nuclear factor erythroid 2-related factor (Nrf2) in breast cancer have been shown to include both pro-oncogenic and anti-oncogenic activities which is influenced, at least in part, by the hormonal env…

lab-animal 2012
Retinoic acid suppresses growth of lesions, inhibits peritoneal cytokine secretion, and promotes macrophage differentiation in an immunocompetent mouse model of endometriosis
Fertility and sterility ·doi:10.1016/j.fertnstert.2012.03.004

OBJECTIVE: To determine the effects of all-trans-retinoic acid (RA) on establishment and growth of endometrial lesions, peritoneal interleukin-6 (IL-6) and macrophage chemotactic factor-1 (MCP-1) concentrations, and CD38, CD11b, and F4/80 e…

lab-animal 2011
Disruption of gap junctions reduces biomarkers of decidualization and angiogenesis and increases inflammatory mediators in human endometrial stromal cell cultures
Molecular and cellular endocrinology ·doi:10.1016/j.mce.2011.04.011

CONTEXT: Uterine decidualization is critical to embryonic implantation and sustained pregnancy. OBJECTIVE: To evaluate the role of gap junction intercellular communications and connexin (Cx) proteins in the morphological and biochemical di…

lab-animal 2010
Retinoic acid is a cofactor for translational regulation of vascular endothelial growth factor in human endometrial stromal cells
Molecular Endocrinology ·doi:10.1210/me.2009-0155

Vascular endothelial growth factor (VEGF) and endometrial angiogenesis play a critical role in successful embryonic implantation. Despite many studies of the effects of estrogen and progesterone on VEGF expression, its focal regulation at t…