Zailong Cai

ORCID: 0000-0003-3132-6823 · 14 papers in corpus
lab-animal 2022
Cell death & disease ·doi:10.1038/s41419-022-05037-8

Endometriosis (EMs) occurs in approximately 50% of women with infertility. The main causes of EMs-related infertility are follicle dysplasia and reduced oocyte quality. Iron overload occurs in ovarian follicular fluid (FF) of patients with …

other 2021
BioMed research international ·doi:10.1155/2021/6464686

OBJECTIVE: To explore the mechanisms of follicular fluids (FFs) on granulose cell (GC) apoptosis in endometriosis-associated infertility. MATERIALS AND METHODS: 60 infertile women were enrolled. The FFs from 30 endometriosis-associated inf…

other 2020
Frontiers in endocrinology ·doi:10.3389/fendo.2020.00391

Purpose: To screen out specific protein with different concentration in follicular fluid from advanced endometriosis and determine its direct effect on mouse oocytes matured in vitro. Methods: FF samples were obtained from 25 patients (EMS …

case-report 2018
OncoTargets and therapy ·doi:10.2147/ott.s162985

BACKGROUND: Ovarian adenosquamous carcinoma is an extremely rare type of ovarian histology. Platinum-refractory disease is also uncommon, but can be fatal because of the lack of available treatment options. To date, there is no study or cas…

review 2017
Evidence-based complementary and alternative medicine : eCAM ·doi:10.1155/2017/5416423

OBJECTIVES: To evaluate the efficacy and safety of Bushen Huoxue prescription (BSHXP) for endometriosis. METHODS: A meta-analysis was performed, and studies were searched from the seven databases from the date of database establishment to …

lab-animal 2015
Evidence-based complementary and alternative medicine : eCAM ·doi:10.1155/2015/269138

Objective. To explore the effects of puerarin to treat endometriosis (EMT) model rats and the possible regulatory mechanisms. Methods. EMT model rats were surgically induced by autotransplantion of endometrial tissues. The appropriate dosag…

lab-animal 2013
The Journal of steroid biochemistry and molecular biology ·doi:10.1016/j.jsbmb.2013.07.006

BACKGROUND AND OBJECTIVES: Puerarin, a phytoestrogen with a weak estrogenic effect, binds to estrogen receptors, thereby competing with 17β-estradiol and producing an anti-estrogenic effect. In our early clinical practice to treat endometri…

lab-animal 2012
PloS one ·doi:10.1371/journal.pone.0045529

BACKGROUND: Puerarin is a major isoflavonoid compound extracted from Radix puerariae. It has a weak estrogenic action by binding to estrogen receptors (ERs). In our early clinical practice to treat endometriosis, a better therapeutic effect…

lab-animal 2011
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719111398500

Phytoestrogens, which have a weak estrogenic effect, bind to estrogen receptors (ERs), thereby competing with estradiol, have an antiestrogenic effect on women of reproductive age with high estrogenic level. Herein, we examined the ability …

lab-animal 2011

Background: Puerarin, a phytoestrogen with a weak estrogenic effect, binds to estrogen receptors, thereby competing with 17b-estradiol (E2) and producing an anti-estrogenic effect. This study was to investigate whether puerarin could suppre…

lab-animal 2011
PloS one ·doi:10.1371/journal.pone.0025011

BACKGROUND: Puerarin, a phytoestrogen with a weak estrogenic effect, binds to estrogen receptors, thereby competing with 17β-estradiol (E2) and producing an anti-estrogenic effect. This study was to investigate whether puerarin could suppre…

other 2010
Fertility and sterility ·doi:10.1016/j.fertnstert.2010.11.039

Cell proliferation of endometrial stromal cells treated with peritoneal fluid of women (aged 25 to 43 years) with endometriosis (n = 12) statistically significantly increased compared with the control treatment (peritoneal fluid of women wi…

lab-animal 2007
Molecular and cellular endocrinology ·doi:10.1016/j.mce.2006.09.012

The expression of Cyp19, the key gene of estrogen biosynthesis, in granulosa cells (GC) is essential for follicular growth and coordination of the ovulatory process. The goal of this study was to examine the effect of PGE2 and PGF2alpha on …

2003
·doi:10.1007/bf02838554