Gina Mantia-Smaldone

AbstractPurpose: Mechanisms of immune dysregulation associated with advanced tumors are relatively well understood. Much less is known about the role of immune effectors against cancer precursor lesions. Endometrioid and clear-cell ovarian …

AbstractPurpose: Mechanisms of immune dysregulation associated with advanced tumors are relatively well understood. Much less is known about the role of immune effectors against cancer precursor lesions. Endometrioid and clear-cell ovarian …

AbstractPurpose: Endometriosis, a largely benign, chronic inflammatory disease, is an independent risk factor for endometrioid and clear cell epithelial ovarian tumors. We aimed to identify plasma miRNAs that can be used to differentiate pa…

AbstractPurpose: Endometriosis, a largely benign, chronic inflammatory disease, is an independent risk factor for endometrioid and clear cell epithelial ovarian tumors. We aimed to identify plasma miRNAs that can be used to differentiate pa…

PDF file - 488K, Supplementary Figure 1: Experimental design. Supplementary Figure 2. Reliability of RNA extraction and reproducibility of RTqPCR techniques. Supplementary Figure 3. Reliability of RT-qPCR assays. Supplementary Figure 4. miR…

PDF file - 488K, Supplementary Figure 1: Experimental design. Supplementary Figure 2. Reliability of RNA extraction and reproducibility of RTqPCR techniques. Supplementary Figure 3. Reliability of RT-qPCR assays. Supplementary Figure 4. miR…

Supplementary Materials and Methods

Supplementary Materials and Methods

PDF file - 36K, Supplementary Table 1. Demographic and clinical characteristics of the study cohort. Supplementary Table 2. List of the 24 miRNAs identified by genome-wide plasma miRNA expression profiling from healthy controls (n=6), endom…

PDF file - 36K, Supplementary Table 1. Demographic and clinical characteristics of the study cohort. Supplementary Table 2. List of the 24 miRNAs identified by genome-wide plasma miRNA expression profiling from healthy controls (n=6), endom…

Suppl Fig S1. Venn diagram of DE genes from 3 group comparisons

Suppl Fig S1. Venn diagram of DE genes from 3 group comparisons

Suppl Fig S2. Kras and Pten pathways in relationship to complement gene expression

Suppl Fig S2. Kras and Pten pathways in relationship to complement gene expression

Suppl Fig S3. Antibody-mediated, complement-induced cytotoxicity

Suppl Fig S3. Antibody-mediated, complement-induced cytotoxicity

Suppl Fig S4. Complement and non-target siRNA

Suppl Fig S4. Complement and non-target siRNA

Suppl Table S1. Differentially expressed genes from different group comparisons

Suppl Table S1. Differentially expressed genes from different group comparisons

Suppl Table S2. Top five canonical pathways from different group comparisons, identified via Ingenuity Pathway Analyses

Suppl Table S2. Top five canonical pathways from different group comparisons, identified via Ingenuity Pathway Analyses

Suppl Table S3. Top five networks from different group comparisons, identified via Ingenuity Pathway Analyses

Suppl Table S3. Top five networks from different group comparisons, identified via Ingenuity Pathway Analyses

PURPOSE: Mechanisms of immune dysregulation associated with advanced tumors are relatively well understood. Much less is known about the role of immune effectors against cancer precursor lesions. Endometrioid and clear-cell ovarian tumors p…