Guiyan Chu

ORCID: 0000-0001-9449-3894 · 2 papers in corpus

lab-animal 2024

UCHL1 promotes the proliferation of porcine granulosa cells by stabilizing CCNB1

Journal of animal science and biotechnology ·doi:10.1186/s40104-024-01043-2

BACKGROUND: The proliferation of porcine ovarian granulosa cells (GCs) is essential to follicular development and the ubiquitin-proteasome system is necessary for maintaining cell cycle homeostasis. Previous studies found that the deubiquit…

lab-animal 2017

Lithium chloride inhibits StAR and progesterone production through GSK-3β and ERK1/2 signaling pathways in human granulosa-lutein cells

Molecular and cellular endocrinology ·doi:10.1016/j.mce.2017.08.018

Lithium chloride (LiCl) is a widely-used medication to treat neurological disorders that has undesirable side effects on the female reproductive system. It has been show that LiCl can inhibit ovarian folliculogenesis, promote follicle atres…