BACKGROUND: Endometrial cancer (EC) is a heterogeneous gynecologic malignancy with distinct histological subtypes and diverse etiological factors. While autoimmune diseases have been associated with cancer development, the causal relationsh…
OBJECTIVE: To investigate the therapeutic effects and mechanisms of curcumin (Cur) in adenomyosis (AM). METHODS: A mouse uterine AM model was established by exposing ICR neonatal mice to tamoxifen (TAM). Female neonatal mice (day 1, n=24) …
BACKGROUND & AIMS: Pancreatitis is influenced by environmental and genetic factors. Genome-wide association studies identified polymorphisms at the X-linked CLDN2 locus as risk factors for chronic pancreatitis. CLDN2 encodes claudin-2 (CLDN…
BACKGROUND: Pelvic inflammatory disease (PID) is a common gynecological disorder that seriously affects women's physical and mental health, yet there are few effective therapeutic options. OBJECTIVE: Mendelian randomization (MR) has been u…
BACKGROUND: Although there are several scoring systems currently used to predict the severity of acute pancreatitis, each of them has limitations. Determine the accuracy of a modified Ranson score in predicting disease severity and prognosi…
OBJECTIVE: To investigate the outcome of total laparoscopic hysterectomy (TLH) and postoperative pain characteristics and compare the pain severity after TLH for adenomyosis or uterine fibroids. METHODS: This prospective observational stud…
OBJECTIVE: This study aimed to explore the optimal time of laparoscopic cystectomy for unilateral ovarian endometrioma patients and evaluate the influence on ovarian reserve. MATERIALS AND METHODS: This prospective randomized controlled st…
Objective: The purpose of this study was to explore the optimal time of laparoscopic cystectomy for unilateral ovarian endometrioma patients and to evaluate the influence on the ovarian reserve. Design: Prospective randomized controlled stu…
OBJECTIVE: To investigate the predictors of residual disease in a hysterectomy following a loop electrosurgical excision procedure (LEEP) for cervical intraepithelial neoplasia (CIN) 3. METHODS: This retrospective study identified 421 pati…
BACKGROUND: Recently, several novel scoring systems have been developed to evaluate the severity and outcomes of acute pancreatitis. This study aimed to compare the effectiveness of novel and conventional scoring systems in predicting the s…
To assess the treatment efficacy of adenomyoma and improvement in implantation receptivity associated with the levonorgestrel-releasing intrauterine system (LNG-IUS) combined with adenomyoma resection. Fifty subjects (control group) underwe…
OBJECTIVE: To assess the utility of hematologic, inflammatory, and immunologic biomarkers for differentiating between ovarian cancer and endometriosis. METHODS: Data were retrospectively reviewed from women diagnosed with ovarian cancer an…
The present meta-analysis aimed to evaluate the effectiveness and safety of puerarin co-treatment with betahistine in treating vertebrobasilar ischemia (VBI) vertigo. A total of 6 medical databases were searched, identifying randomized cont…
Objective To investigate the effects of qi-enriching and blood-activating herbs on expressions of IL-2 and IL-6 in ectopic endometrium rats.Methods The model of endometriosis in rats was duplicated.After three weeks,the rats were randomly d…