L Aghajanova

No ORCID on file · 6 papers in corpus · active 2008-2022

Study types

  • article 5
  • book-chapter 1

Condition tags

  • endometriosis 6
  • mesh:D004715 4
  • infertility 4
article 2022
The mid-secretory endometrial transcriptomic landscape in endometriosis: a meta-analysis
Human reproduction open ·doi:10.1093/hropen/hoac016

STUDY QUESTION: Do women with endometriosis have a different endometrial gene expression profile at the time of embryo implantation than women without endometriosis? SUMMARY ANSWER: The endometrial gene expression profile of women with endo…

article 2011
Nuclear Receptor, Coregulator Signaling, and Chromatin Remodeling Pathways Suggest Involvement of the Epigenome in the Steroid Hormone Response of Endometrium and Abnormalities in Endometriosis
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719111415546
book-chapter 2010
Global Expression Analysis of Nuclear Receptors and Co-Regulators Reveals DNA Acetylation and Methylation and Select Gene and Signaling Pathway Dysregulation in Eutopic Endometrium of Women with Endometriosis.
·doi:10.1210/endo-meetings.2010.part3.p7.p3-350
article 2010
Unique Transcriptome, Pathways, and Networks in the Human Endometrial Fibroblast Response to Progesterone in Endometriosis
Biology of reproduction ·doi:10.1095/biolreprod.110.086181

Eutopic endometrium in endometriosis has molecular evidence of resistance to progesterone (P(4)) and activation of the PKA pathway in the stromal compartment. To investigate global and temporal responses of eutopic endometrium to P(4), we c…

article 2009
MicroRNA expression profiling of eutopic secretory endometrium in women with versus without endometriosis
Molecular human reproduction ·doi:10.1093/molehr/gap068

Endometriosis is a common gynecologic disorder characterized by pain and infertility. In addition to estrogen dependence, progesterone resistance is an emerging feature of this disorder. Specifically, a delayed transition from the prolifera…

article 2008
Steroidogenic Enzyme and Key Decidualization Marker Dysregulation in Endometrial Stromal Cells from Women with Versus Without Endometriosis1
Biology of reproduction ·doi:10.1095/biolreprod.108.070300

Identification of mechanisms underlying endometriosis pathogenesis will facilitate understanding and treatment of infertility and pain associated with this disorder. Herein, we investigated the expression of steroidogenic pathway enzymes an…