Lea Ruoso

No ORCID on file · 3 papers in corpus
rct 2026
Differential Impact of the Endometrial Immune Environment in Fresh Versus Frozen Embryo Transfer
Cells ·doi:10.3390/cells15131186

BACKGROUND: The endometrial immune environment regulates maternal immune tolerance and plays a key role in embryo implantation. We investigated whether its impact on reproductive outcomes differs between fresh and frozen embryo transfer (FE…

observational 2026
Using endometrial immune profiling in young IVF patients: implantation rates improved for morphologically sub-optimal embryos
Frontiers in immunology ·doi:10.3389/fimmu.2026.1706032

INTRODUCTION: A balanced endometrial immune profile is considered to be the ideal environment for a successful implantation, as opposed to endometrial immune dysregulation. However, the embryo quality may be the pivotal 'immune' factor comp…

rct 2025
Endometrial immune profiling and precision therapy increase live birth rate after embryo transfer: a randomised controlled trial
Frontiers in immunology ·doi:10.3389/fimmu.2025.1523871

INTRODUCTION: Despite advancements in assisted reproductive treatments, 70% of transferred embryos fail to implant successfully, yielding significant personal and global repercussions. One promising avenue of research is to take into accoun…