Isabel Lorenzo

No ORCID on file · 2 papers in corpus

lab-animal 2024

Machine learning in time-lapse imaging to differentiate embryos from young vs old mice†

Biology of reproduction ·doi:10.1093/biolre/ioae056

Time-lapse microscopy for embryos is a non-invasive technology used to characterize early embryo development. This study employs time-lapse microscopy and machine learning to elucidate changes in embryonic growth kinetics with maternal agin…

lab-animal 2021

Reproductive Outcomes from Maternal Loss of Nlrp2 Are Not Improved by IVF or Embryo Transfer Consistent with Oocyte-Specific Defect

Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1007/s43032-020-00360-x

Nlrp2 encodes a protein of the oocyte subcortical maternal complex (SCMC), required for embryo development. We previously showed that loss of maternal Nlrp2 in mice causes subfertility, smaller litters with birth defects, and growth abnorma…