Shuqiang Chen

ORCID: 0000-0002-2505-4174 · 4 papers in corpus
other 2026
Temporal trajectory of plasma miRNA during the peri-implantation stage: comparing implantation success and failure in single frozen-thawed blastocyst transfers
Frontiers in endocrinology ·doi:10.3389/fendo.2026.1708664

BACKGROUND: Implantation failure is the most common cause of pregnancy failure and is a major limiting factor in assisted reproduction. Plasma microRNA (miRNA) expression profiles show dynamic changes among individuals with successful impla…

lab-animal 2024
Increased levels of villus-derived exosomal miR-29a-3p in normal pregnancy than uRPL patients suppresses decidual NK cell production of interferon-γ and exerts a therapeutic effect in abortion-prone mice
Cell communication and signaling : CCS ·doi:10.1186/s12964-024-01610-0

OBJECTIVE: Recurrent pregnancy loss (RPL) patients have higher absolute numbers of decidual natural killer (dNK) cells with elevated intracellular IFN-γ levels leading to a pro-inflammatory cytokine milieu, which contributes to RPL pathogen…

lab-animal 2024
MiR-135a-5p regulates window of implantation by suppressing pinopodes development and decidualization of endometrial stromal cells
Journal of assisted reproduction and genetics ·doi:10.1007/s10815-024-03088-8

PURPOSE: The window of implantation (WOI) is a brief period during which the endometrium is receptive to embryo implantation. This study investigated the relationship between miR-135a-5p and endometrial receptivity. METHODS: Peripheral blo…

lab-animal 2024
TSG6-Exo@CS/GP Attenuates Endometrium Fibrosis by Inhibiting Macrophage Activation in a Murine IUA Model
Advanced materials (Deerfield Beach, Fla.) ·doi:10.1002/adma.202308921

Intrauterine adhesion (IUA) is characterized by the formation of fibrous scar tissue within the uterine cavity, which significantly impacts female reproductive health and even leads to infertility. Unfortunately, severe cases of IUA current…