Georgina M Chambers

OBJECTIVE: To estimate the total number of infants born globally between 1978 and 2018 after assisted reproductive technology (ART). Estimates are based on epidemiological data systematically and uniquely collected by the International Comm…

OBJECTIVE: To report the utilization, effectiveness, and safety of assisted reproductive technologies (ARTs) in 2019. DESIGN: A retrospective, cross-sectional survey derived from cycle and pregnancy outcome data submitted by national and r…

OBJECTIVE: To report utilization, effectiveness, and safety of assisted reproductive technologies in 2015 and 2016. DESIGN: A retrospective, cross-sectional survey of 3,103 assisted reproductive technology clinics in 74 countries in 2015 a…

STUDY QUESTION: Is the live birth rate higher for cleavage stage embryos compared to blastocysts in patients with a single zygote following oocyte fertilization using IVF or ICSI? SUMMARY ANSWER: Among patients with only a single zygote, t…

STUDY QUESTION: What updates of the International Glossary on Infertility and Fertility Care are required, to reflect contemporary scientific knowledge, social needs, and inclusive definitions, while harmonizing international communication …

STUDY QUESTION: How do cumulative live birth rates (CLBRs) in women with endometriosis compare to those with other infertility diagnoses undergoing ART? SUMMARY ANSWER: Women with endometriosis as the sole cause of infertility achieved hig…

STUDY QUESTION: What is the incidence of and risk factors for monozygotic twinning (MZT) following single embryo transfer (SET) in ART cycles in Australia and New Zealand? SUMMARY ANSWER: MZT occurred in 1.5% of live births following SET, …

OBJECTIVE: To evaluate whether perinatal and infant outcomes differ between singleton births after assisted reproductive technology (ART) in women with endometriosis alone and those with other causes of infertility. DESIGN: Population-base…

BACKGROUND: Family-planning policies have focused on contraceptive approaches to avoid unintended pregnancies, postpone, or terminate pregnancies and mitigate population growth. These policies have contributed to significantly slowing world…

STUDY QUESTION: Can we develop a prediction model for the chance of a live birth following the transfer of an embryo created using donated oocytes? SUMMARY ANSWER: Three primary models that included patient, past treatment, and cycle chara…

Researchers interested in causal questions must deal with two sources of error: random error (random deviation from the true mean value of a distribution), and bias (systematic deviance from the true mean value due to extraneous factors). F…

STUDY QUESTION: What is the association between a country's level of gender equality and access to ART, as measured through ART utilization? SUMMARY ANSWER: ART utilization is associated with a country's level of gender equality even after…

STUDY QUESTIONS: In couples with unexplained infertility and a poor prognosis of natural conception, are four cycles of IUI with ovarian stimulation (IUI-OS) non-inferior to one completed cycle of IVF for the outcome of cumulative live birt…

STUDY QUESTION: Can consensus definitions for the core outcome set for infertility be identified in order to recommend a standardized approach to reporting? SUMMARY ANSWER: Consensus definitions for individual core outcomes, contextual sta…