OBJECTIVES: To investigate associations between current use of menopausal hormone therapy and development of venous thromboembolism, ischaemic stroke, and myocardial infarction. DESIGN: Nationwide nested case-control study. SETTING: Natio…
BACKGROUND: Cardiovascular disease risk accelerates in women after the menopausal transition, coinciding with the cessation of endogenous oestrogen production. The accompanying decline in vascular function is considered a key driver of this…
PURPOSE: To investigate the association between hormonal contraceptive use and the risk of retinal vascular occlusions in women of reproductive age. DESIGN: Register-based, nationwide cohort study. PARTICIPANTS: A total of 2,208,172 women…
Intracytoplasmic sperm injection (ICSI) and conventional in vitro fertilization (c-IVF) are widely used fertilization techniques in assisted reproduction, but their relative effectiveness in patients without severe male factor infertility r…
OBJECTIVE: To evaluate the association between contemporary hormonal contraceptive use and the risk of incident ischaemic stroke and myocardial infarction. DESIGN: Real-world, nationwide, prospective cohort study. SETTING: Denmark, by use…
BACKGROUND: Infertility affects 15%-25% of all couples during their reproductive life span. It is a significant societal and public health problem with potential psychological, social, and economic consequences. Furthermore, infertility has…