Xiaoying He

Accurate pathway activity inference from single-cell RNA sequencing (scRNA-seq) data is hindered by sparsity, technical noise, and the weak yet coordinated nature of transcriptional programs. Existing methods typically aggregate expression …

BACKGROUND: Endometriosis (EM) may be associated with adverse pregnancy outcomes, but its relationship with gestational diabetes mellitus (GDM) and circulating metabolic biomarkers remains incompletely defined. This study evaluated temporal…

Endometriosis‑associated infertility is considered to be linked to cellular senescence. The present study assessed whether rapamycin, a senescence inhibitor, ameliorates endometriosis‑associated infertility by upregulating peroxisome prolif…

Severe endometrial injury caused by invasive uterine operation and/or endometritis often results in intrauterine adhesions (IUAs), which are named Asherman's syndrome (AS), further leading to menstrual disorders, infertility and severe comp…

Recent data support a role for SHARP1, a basic helix-loop-helix transcription repressor, in the regulation of malignant cell behavior in several human cancers. However, the expression and role of SHARP1 during the development of endometrial…