Afshar S

ORCID: 0000-0001-5136-4259 · 4 papers in corpus
lab-animal 2021
Deferoxamine preconditioning enhances the protective effects of stem cells in streptozotocin-induced Alzheimer's disease
Life sciences ·doi:10.1016/j.lfs.2021.120093

AIMS: Stem cell-based therapy is one of the promising strategies in the treatment of Alzheimer's disease (AD), but the short lifespan and low homing of transplanted cells continue to be a major obstacle in this method. Preconditioning of st…

lab-animal 2021
Synergistic effects of adipose-derived mesenchymal stem cells and selenium nanoparticles on streptozotocin-induced memory impairment in the rat
Life sciences ·doi:10.1016/j.lfs.2021.119246

AIMS: Memory impairment is determined to be the most well-known symptom of Alzheimer's disease (AD). Although cell therapy seems is an efficient therapeutic strategy to attenuate the AD-related memory impairment, transplanted cells have a s…

lab-animal 2018
Amelioration of diabetes-induced testicular and sperm damage in rats by cerium oxide nanoparticle treatment
Andrologia ·doi:10.1111/and.13089

Cerium oxide nanoparticles (CNPs) as an antioxidant have been used frequently to attenuate hyperglycaemia oxidative damage in different organs. We investigated the impact CNPs on the qualitative and quantitative sperm parameters, spermatoge…

lab-animal 2018
Sublethal concentration of H2O2 enhances the protective effect of mesenchymal stem cells in rat model of spinal cord injury
Biotechnology letters ·doi:10.1007/s10529-017-2499-7

OBJECTIVE: To investigate the effect of H2O2 on the migration and antioxidant defense of mesenchymal stem cells (MSCs) and the neurotrophic effects of H2O2-treated MSCs on spinal cord injury (SCI). RESULTS: Sublethal concentrations of H2O2…