Fei Liu

OBJECTIVE: To address the urgent need for non-invasive diagnosis of  endometriosis, this study developed a novel microfluidic platform utilizing a three-dimensional (3D) polydimethylsiloxane scaffold microchip to efficiently capture circula…

Objective: To assess the global, regional, and national burden and trends of endometriosis-related infertility in women of reproductive age. Methods: Data were extracted from the Global Burden of Disease Study 2021. We analyzed the number o…

BACKGROUND: Endometriosis is a chronic inflammatory disorder that significantly compromises women's health, typically manifesting as pelvic pain and/or infertility. This condition imposes a substantial burden on global healthcare systems. …

BackgroundEndometriosis is a chronic inflammatory disorder that significantly compromises women's health, typically manifesting as pelvic pain and/or infertility. This condition imposes a substantial burden on global healthcare systems.Meth…

Fei Liu,1,2,* Suzhen Yuan,1,2,* Qing Yan,1,2 Shuhao Yang,1,2 Wei Yan,1,2 Tao Xiang,1,2 Zhangying Wu,3 Guirong Li,3 Wu Ren,1,2 Wenwen Wang1,2 1Department of Obstetrics and Gynecology, National Clinical Research Center for Obstetrics …

RATIONALE: Ovarian clear cell carcinoma (OCCC) during pregnancy is exceedingly rare, particularly when accompanied by squamous differentiation, with only a limited number of cases reported in the English literature to date. PATIENT CONCERN…

Ectopic pancreas (EP) is most commonly located in the upper gastrointestinal tract, particularly in the stomach. Malignant transformation of EP is exceptionally rare, and due to its very low incidence, the response to drug therapy and overa…

OBJECTIVE: Oral squamous cell carcinoma remains difficult to treat because of its marked tumor heterogeneity, highlighting the need to identify molecular subtypes with distinct therapeutic vulnerabilities. This study aimed to comprehensivel…

The aim of this study was to investigate the effects of puerarin (Pue), a phytoestrogen, on the production performance, egg quality, endocrine hormones, antioxidant capacity, and intestinal morphology in aged laying hens. A total of 180 Hy-…

Epithelial ovarian cancer (EOC) is the deadliest women's cancer and has a poor prognosis. Early detection is the key for improving survival (a 5-year survival rate in stage I/II is over 70% compared to that of 25% in stage III/IV) and can b…

OBJECTIVE: The study aimed at investigating the association between the vascular endothelial growth factor A (VEGFA) genetic variants, the VEGFA serum level, and the primary ovarian insufficiency (POI) risk in Chinese Han women. DESIGN: An…

BACKGROUND: It has long been appreciated that different subtypes (serous, clear cell, endometrioid and mucinous) of epithelial ovarian carcinoma (EOC) have distinct pathogenetic pathways. However, clinical management, especially chemotherap…

Adenomyosis, defined as ectopic endometrial tissue within the myometrium, can often be misdiagnosed as multiple uterine leiomyomata or endometrial thickening. We therefore performed a combined mRNA and long noncoding (lnc)RNA microarray and…

Estrogen receptor-alpha (ER-α) polymorphisms have been hypothesized to be associated with the risk of endometriosis (EMT) development by many epidemiological studies, however, the available results were conflicting. To derive a more precise…