Eleftherios P. Diamandis

ORCID: 0000-0002-1589-820X · 11 papers in corpus
review 2020
BMC medicine ·doi:10.1186/s12916-020-01763-y

BACKGROUND: It has long been known that mutations are at the core of many diseases, most notably cancer. Mutational analysis of tissues and fluids is useful for cancer and other disease diagnosis and management. MAIN BODY: The prevailing c…

other 2018
F1000Research ·doi:10.12688/f1000research.13863.2

Background: To elucidate potential markers of endometriosis and endometriosis-associated endometrioid and clear cell ovarian carcinomas using mass spectrometry-based proteomics. Methods: A total of 21 fresh, frozen tissues from patients dia…

2018
·doi:10.12688/f1000research.13863.1

Background: To elucidate potential markers of endometriosis and endometriosis-associated endometrioid and clear cell ovarian carcinomas using mass spectrometry-based proteomics. Methods: A total of 21 fresh, frozen tissues from patients …

diagnostic-accuracy 2017
BMC medicine ·doi:10.1186/s12916-017-0817-5

BACKGROUND: TEX101 is a cell membrane protein exclusively expressed by testicular germ cells and shed into seminal plasma. We previously verified human TEX101 as a biomarker for the differential diagnosis of azoospermia, and developed a fir…

lab-animal 2016
·doi:10.1158/1557-3265.ovca15-b13

Abstract Introduction and Objectives: It is evident that ovarian cancer (OvCa) is not a single disease but is made up of several distinct subtypes, including serous, endometrioid, clear cell and mucinous. The gold-standard biomarker CA125 p…

other 2013
Clinical chemistry ·doi:10.1373/clinchem.2012.187047
other 2012
Clinical biochemistry ·doi:10.1016/j.clinbiochem.2012.08.011

OBJECTIVES: To measure the levels of serum CUB and zona pellucida-like domain-containing protein 1 (CUZD1) in patients with ovarian cancer (OvCa), benign gynecological conditions and healthy women and in a number of other cancer types (brea…

diagnostic-accuracy 2010
Clinical biochemistry ·doi:10.1016/j.clinbiochem.2009.10.012

OBJECTIVES: New ovarian cancer biomarkers suitable for early disease diagnosis, prognosis or monitoring could improve patient management and outcomes. DESIGN AND METHODS: Nidogen-2 was measured by immunoassay in serum of 100 healthy women,…

other 2009
Molecular & cellular proteomics : MCP ·doi:10.1074/mcp.m800313-mcp200

Current ovarian cancer biomarkers are inadequate because of their relatively low diagnostic sensitivity and specificity. There is a need to discover and validate novel ovarian cancer biomarkers that are suitable for early diagnosis, monitor…

other 2008
British journal of cancer ·doi:10.1038/sj.bjc.6604630

Currently, there are no effective biomarkers for ovarian cancer prognosis or prediction of therapeutic response. The objective of this study was to examine a panel of 10 serum biochemical parameters for their ability to predict response to …

other 2007
British journal of cancer ·doi:10.1038/sj.bjc.6603556

The human tissue kallikrein family (KLK for protein; KLK for gene) includes 15 members. Twelve kallikreins, including KLK6, are concurrently upregulated in ovarian cancer. However, the mechanism of this phenomenon remains unclear. In this s…