Kathleen M. Egan

Gender-specific incidence patterns and the presence of hormonal receptors on tumor cells suggest that sex hormones may play a role in the onset of primary brain tumors. However, epidemiological studies on the relation of hormonal risk facto…

OBJECTIVE: To estimate whether the protective effect of premenopausal bilateral oophorectomy on breast cancer risk is mitigated by estrogen therapy use after surgery. METHODS: In pooled data from four population-based case-control studies …

Bilateral oophorectomy is often performed during hysterectomy for benign conditions and can reduce breast cancer risk by 20%-50% when performed at younger ages. Accuracy of estimating the decrease in breast cancer risk associated with bilat…

Abstract Background: Bilateral oophorectomy at early ages (<40 years) is recognized to lower breast cancer risk. Among U.S. women, oophorectomy is often performed with hysterectomy for benign conditions such as endometriosis and uterine …

Bilateral oophorectomy is often performed during hysterectomy for benign conditions and can reduce breast cancer risk by 20%–50 % when performed at younger ages. Accuracy of estimating the decrease in breast cancer risk associated with bila…

OBJECTIVE: To clarify the hormonal context of breast cancer etiology we used data from a large, population-based case-control study to investigate the relationship between breast cancer risk and a history of diabetes mellitus, disorders ass…