OBJECTIVE: To investigate the clinical efficacy and potential mechanisms of Traditional Chinese Medicine (TCM) combined with High-Intensity Focused Ultrasound (HIFU) in the treatment of adenomyosis, providing evidence-based support for opti…
This study aims to assess associations of dyslipidemia with in vitro fertilization/intracytoplasmic sperm injection outcomes in women undergoing their first ovarian stimulation and whether age, body mass index, or lipid levels modify these …
The human endometrial immune landscape is critical for homeostasis and pregnancy success, yet its dynamic remodeling across the menstrual cycle and in pathology remains poorly characterized. Here, we construct a comprehensive immune cell at…
OBJECTIVE: To introduce a novel hysteroscopic suture fixation technique using a "pre-fabricated knot". This is used for levonorgestrel-releasing intrauterine system placement in adenomyosis treatment. DESIGN: Step-by-step video of "pre-fab…
BACKGROUND: Chronic endometritis (CE) has been associated with implantation failure and recurrent reproductive failure. Antibiotic therapy is widely used as a first-line treatment for CE, and previous studies have suggested that successful …
It has been proved that lipids have an effect on endometriosis, and the plasma atherosclerosis index (AIP), as a new lipid index, has not been proved to be correlative to endometriosis. The National Health and Nutrition Examination Survey f…
Outer membrane vesicles (OMVs) are nanoscale vesicles actively released by Gram-negative bacteria, and have become key mediators in bacterial physiology, host-pathogen interactions, and disease pathogenesis. The biogenesis of OMVs is a dyna…
Background/Objectives: The diagnosis of endometriosis (EM) remains challenging due to the lack of a perfect diagnostic standard and the poor concordance between clinical symptoms and lesion severity. Although laparoscopy is widely used in c…
OBJECTIVE: To investigate the complementary roles of rectal magnetic resonance imaging and endoscopic ultrasound in the preoperative assessment of rectal deep endometriosis (DE). DESIGN: Retrospective, cross-sectional study. SETTING: Shen…
Endometrial carcinoma, a prevailing malignancy of the female reproductive system, exhibits escalating incidence and a trend towards early onset. Hormone therapy serves as a primary choice for fertility preservation and is also considered fo…
The homeostasis balance of copper, as an essential trace element for life activities, is crucial for maintaining the normal function of cells. Cuproptosis, discovered in recent years, is a novel type of programmed cell death triggered by th…
Uterine cancer (UC) is the most common malignancy of the female reproductive system worldwide, with a continuously rising incidence, posing a significant public health challenge. This study systematically evaluated the burden of UC using th…
BACKGROUND: Polycystic ovary syndrome (PCOS) has been associated with adverse pregnancy outcomes; however, current literature presents inconsistent findings, probably due to varying feotal numbers included in previous research. This study s…
BackgroundOvarian cancer (OC) remains highly lethal due to frequent late-stage diagnosis and the challenge of distinguishing malignant from benign adnexal masses (BAM) preoperatively. Reliable non-invasive diagnostic biomarkers remain an un…
BACKGROUND: First implantation failure (FIF) remains a significant challenge in in vitro fertilization/intracytoplasmic sperm injection-embryo transfer (IVF/ICSI-ET), and a considerable proportion of affected women subsequently progress to …
BACKGROUND: Endometriosis is a systemic gynecological disorder affecting ~ 10% of reproductive-aged women and shares pathophysiological features with cardiovascular disease (CVD). However, its associations with cardiac remodeling and CVD ri…
Fibroblast growth factor receptor 2 (FGFR2) has emerged as a highly promising therapeutic target due to its critical role in the pathogenesis and progression of endometriosis. To date, a variety of FGFR2 inhibitors have exhibited remarkable…
Accumulating observational evidence suggests an association between thyroid function and endometriosis, though the causal relationship remains unclear. To investigate potential bidirectional causal relationships, including for endometriosis…
PurposeThis study aimed to conduct a comprehensive bibliometric analysis to characterize global research patterns, scientific output, and emerging trends in the treatment of female chronic pelvic pain (CPP).MethodsPublications related to fe…
Premature ovarian failure (POF) is characterized by abnormal ovulatory and ovarian endocrine functions in women before the age of 40, and is a leading cause of female infertility. Currently, effective drug treatments for this condition rema…
Lactic acid modification of histones represents an emerging post-translational modification that establishes a critical link between cellular metabolic reprogramming and epigenetic regulation through the covalent binding of lactic acid to h…