Priscila O. Carvalho

lab-animal 2025

Methotrexate carried in lipid core nanoparticles reduces microglial activation and induces neuroprotection after cortical stroke induced in rats

Clinics (Sao Paulo, Brazil) ·doi:10.1016/j.clinsp.2025.100676

Background This study aimed to investigate the effects of LDE-MTX on acute cerebral infarction. The study focuses on how LDE-MTX can influence the outcomes of ischemic stroke in a rat model, specifically examining its neuroprotective proper…

other 2019

Nanotechnology for the treatment of deep endometriosis: uptake of lipid core nanoparticles by LDL receptors in endometriotic foci

Clinics (Sao Paulo, Brazil) ·doi:10.6061/clinics/2019/e989

OBJECTIVE: Rapidly dividing cells in multiple types of cancer and inflammatory diseases undergo high low density lipoprotein (LDL) uptake for membrane synthesis, and coupling an LDL-like nanoemulsion, containing lipid nanoparticles (LDE) to…

observational 2016

mRNA levels of low-density lipoprotein receptors are overexpressed in the foci of deep bowel endometriosis

Human Reproduction ·doi:10.1093/humrep/dew303

STUDY QUESTION: Is mRNA expression of LDL receptors altered in deep bowel endometriotic foci? SUMMARY ANSWER: mRNA expression of LDL receptors is up-regulated in deep bowel endometriotic foci of patients with endometriosis. WHAT IS KNOWN A…