L D Boada — Endo Lab

lab-animal 1996

Identification of a specific binding site for the anabolic steroid stanozolol in male rat liver microsomes

The Journal of pharmacology and experimental therapeutics ·doi:10.1016/s0022-3565(25)21269-1

Male rat liver microsomes contain a [3H]dexamethasone binding site, capable of binding glucocorticoids and progesterone. We have shown previously that the 17 alpha-alkylated androgen, stanozolol, can inhibit the [3H]dexamethasone binding to…

lab-animal 1995

[3H]dexamethasone binding activity in liver microsomes is modulated differently by 17 alpha-alkylated androgens and testosterone in vivo

Pharmacology & toxicology ·doi:10.1111/j.1600-0773.1995.tb01025.x

Rat liver microsomes contain a single class of steroid binding sites, capable of binding various glucocorticoids and progesterone. In a previous article, we have described the in vitro interaction of several androgens with this binding site…

lab-animal 1994

Stanozolol and danazol, unlike natural androgens, interact with the low affinity glucocorticoid-binding sites from male rat liver microsomes

Endocrinology ·doi:10.1210/endo.134.3.8119180

Some 17 alpha-alkylated androgens used as anabolic agents, such as stanozolol (ST) and danazol (DA), have specific effects on the liver that are not exerted by testosterone. This gives rise to the possibility that a steroid-binding protein,…