L Zhang

Endometriosis is a common gynecological disease with high recurrence rates after surgery and the lesions keep unlimited proliferative capacity. The effect of garcinol on cell proliferation has not been investigated in endometriosis. Herein,…

Objective: To investigate the inhibitory effects of phloroglucinol on eutopic stromal cells and ectopic stromal cells from endometriosis and its molecular mechanism. Methods: The effect of phloroglucinol on the survival rate of endometriosi…

Abstract Study question Can a standardised hospital-school collaborative model improve early detection and multidisciplinary management of adolescent dysmenorrhea and suspected early-onset endometriosis? Summary answer Yes, this model signi…

Objective: To analysis the safety and feasibility of laparoscopic total hysterectomy in patients with obliterated rectouterine pouch. Methods: A retrospective analysis was conducted on 197 patients who underwent laparoscopic total hysterect…

Endometrial tolerance is a key factor for successful embryo implantation and endometrial thickness is an important clinical indicator for its evaluation. The incidence of thin endometrium in IVF is 2.4%, and most studies have shown that cli…

Objective: To investigate the clinical features, diagnosis and treatment of oblique vaginal septum syndrome (OVSS). Methods: The clinical data of 80 patients with OVSS admitted to The Second Hospital of Hebei Medical University from July 20…

PURPOSE: The purpose of this study was to perform a meta-analysis comparing the short-term and long-term outcomes in laparoscopic groin hernia repair with or without preservation of the uterine round ligament (URL) in females. METHODS: We …

中肾样腺癌是一种新近报道的罕见女性生殖系统肿瘤，因其组织学特点、免疫表型及分子改变均类似于起源于中肾管残件的宫颈中肾腺癌而得名，但是中肾样腺癌多发生于缺乏中肾管残件的子宫体和卵巢。因卵巢中肾样腺癌往往与子宫内膜异位症或苗勒管肿瘤相关而被认为其可能起源于苗勒管。中肾样腺癌多样性的组织结构与多种肿瘤形态存在交叉，极易误诊。现报道1例曾被误诊为尿路上皮癌的膀胱中肾样腺癌。本文将阐述其临床病理特征及鉴别诊断，并对中肾样腺癌起源加以探讨，以提高在临床诊疗过程中对该疾病的认识，避免漏诊误…

Objectives: Endometriosis is a common gynecological disease affecting up to ~10% of women at reproductive age. Prior combined studies implied that MARVELD2 might be involved in the pathogenesis of certain malignancies. Here, 211 Han Chinese…

Objective: To investigate the relationship between the clinical efficacy and the ablated area of endometrium in patients with internal adenomyosis treated with focused ultrasound ablation surgery (FUAS). Methods: From January 2015 to Decemb…

Objective: To analyze the labor progression characteristics of primiparous term singleton pregnant women with adenomyosis. Methods: From April 2014 to May 2021, pregnant women underwent regular antenatal examination in Peking University Thi…

Background.In the bone marrow microenvironment of postmenopausal osteoporosis (PMOP), bone marrow mesenchymal stem cell (BMSC)-derived exosomal miRNAs play an important role in bone formation and bone resorption, although the pathogenesis h…

OBJECTIVE: Exosomes play crucial roles in cell-cell communication, but few studies exist on the role of exosomal miRNA in the interaction between peritoneal macrophages (pMφ) and human ectopic endometrial stromal cells (eESCs) in endometrio…

Background. Endometriosis (EMs) is a non-malignant gynecological disease, whose pathogenesis remains to be clarified. Recent studies have found that hypoxia induces epithelial-mesenchymal transition (EMT) as well as epigenetic modification …

Objective: To explore the relationship between different types of female reproductive system dysplasia and age of visit, clinical manifestations, common types of combined malformations and endometriosis. Methods: The patient's medical recor…

OBJECTIVE: To assess the effects of fertiloscopy procedure on the outcomes of subsequent in vitro fertilization cycles in patients with repeated implantation failure (RIF). METHODS: A retrospective study was performed on 50 patients underw…

Over the last two decades, remarkable progress has been made in treating patients with benign gynaecological diseases using minimally invasive or non-invasive treatment techniques. The progress is related not only to novel modalities, but a…

OBJECTIVE: To discuss the therapy for ureteral endometriosis. METHODS: The clinical data of 25 cases of histopathologically confirmed ureteral endometriosis during 2001-2015 were retrospectively analyxed. RESULTS: In the 25 cases, all the…

OBJECTIVE: To discuss the therapy for ureteral endometriosis. METHODS: The clinical data of 25 cases of histopathologically confirmed ureteral endometriosis during 2001-2015 were retrospectively analyxed. RESULTS: In the 25 cases, all the p…

OBJECTIVE: Adenomyosis is a common benign gynecological disease which has some malignant behaviors. Programmed cell death 4 (PDCD4) is a newly identified tumor suppressor gene which lowly expresses in various cancers. However, the expressio…

BACKGROUND: The pathogenesis of endometriosis remains poorly defined. The aberrant angiogenesis that occurs in eutopic endometrium may play a role in the lesion formation and survival. The difference in gene expression profile between human…

Objective: To evaluate the diagnostic value of color Doppler flow imaging for polypoid lesions of gallbladder. Methods:The features of ultrasonographic imaging of 56 cases were analyzed, including 38 with cholysterol polyp, 7 with ade-nomyo…