Hye Sung Moon

OBJECTIVE: Endometriosis is a common and recurring gynecologic disease which have afflicting females of reproductive age. We investigated the efficacy of long-term, post-operative use of dienogest for ovarian endometrioma. METHODS: We stud…

Objective: To compare perioperative outcomes of robotic single-site (RSS) surgery with conventional single-port laparoendoscopic surgery for the treatment of advanced-stage endometriosis. Materials and Methods: This is a retrospective cohor…

OBJECTIVE: Adenomyosis and endometriosis are relatively common gynecological diseases that exhibit many common features. This study identified gynecological and non-gynecological diseases that exhibited comorbidity with adenomyosis and endo…

목적: 자궁내막증은 자궁 밖의 다른 조직, 특히 복막, 난소, 직장질격막 등에 샘과 버팀질을 포함한 기능성의 자궁내막조직이 존재하는 질환을 말한다. 정확한 병인은 알려지지 않고 있지만 생리 중 역류한 자궁혈이 자궁 외 조직에 착상해 발생하는 것으로 생각되며 이 과정에는 혈관내피세포성장인자 (vascular endothelial cell growth factor, VEGF)가 중요한 역할을 하고 있는 것으로 보인다. 본 연구는 …

OBJECTIVE: To investigate whether single nucleotide polymorphisms and its haplotypes of gene encoding CYP1B1 are associated with the risk of advanced endometriosis in Korean women. METHODS: We investigated 221 patients with histopathologic…

Objective: To investigate whether polymorphism of CYP17 gene is associated with the risk of advanced endometriosis in Korean women. Methods: The 194 endometriosis patients and 209 controls were enrolled. Blood samples were collected from 19…

Objective To investigate whether polymorphism of gene encoding estrogen receptor-α is associated with the risk of endometriosis in Korean women. Material and Methods We investigated 136 patients with histopathologically confirmed endometrio…

Objective : Enzymes belonging to the Glutathione S transferase and cytochrome P450 families are involved in the two-stage detoxification process of a number of pro-carcinogens. We genotyped each 74 women with moderate or severe endometriosi…

Objective : The aim of this study was to examine whether polymorphic variation in GSTs confers susceptibility to Endometriosis in Korean populations. Methods : The GSTM1, GSTT1, and GSTP1 genotypes were determined in 124 patients with Endom…

OBJECTIVE: To investigate expression of matrix metalloproteinase-2 (MMP-2), membranous type 1 matrix metalloproteinase (MT1-MMP), and tissue inhibitor of metalloproteinase-2 (TIMP-2) in ectopic and eutopic endometrium from women with and wi…

Endometriosis is characterized by the ectopic implantation of endometrium on peritoneal surfaces. Angiogenic and growth factors may play a significant role in the pathogenesis of endometriosis. Midkine (MK) and pleiotrophin (PTN) are two re…