Li Yan

No ORCID on file · 13 papers in corpus · active 2005-2025

Study types

  • article 8
  • other 5

Condition tags

  • endometriosis 9
  • mesh:D004715 8
  • adenomyosis 4
  • infertility 2
  • endometrioma 1
  • dysmenorrhea 1
  • dyspareunia 1
other 2025
Reproductive biomedicine online ·doi:10.1016/j.rbmo.2024.104499

RESEARCH QUESTION: How does tubal endometriosis (TEM) impact the morphology and ultrastructure of tubal epithelium, and what are the underlying pathophysiological mechanisms of TEM? DESIGN: Epithelial samples of fallopian tube were collect…

article 2025
Reproduction (Cambridge, England) ·doi:10.1530/rep-25-0158

In brief: There is no ideal animal model of adenomyosis, which reflects the imperfect understanding of complex human pathogenesis. In this study, we successfully induced adenomyosis in a mouse model via sharp-blunt trauma, which more closel…

other 2024
International journal of nanomedicine ·doi:10.2147/IJN.S456594

INTRODUCTION: Endometriosis (EM) is an estrogen-dependent benign gynecologic disease affecting approximately 10% of reproductive-age women with a high recurrence rate, but lacks reliable biomarkers. No previous studies have investigated the…

article 2024
Journal of reproductive immunology ·doi:10.1016/j.jri.2024.104415

Endometriosis and adenomyosis have common pathogenesis and close relationship, with multi-factors involved in related infertility and IVF failure. They lead to anatomical changes, ovarian reserve reduction, endocrine abnormalities, altered …

other 2023
Journal of proteomics ·doi:10.1016/j.jprot.2023.104995

Endometriosis is a gynecological disease related to menstruation that affects nearly 10% of reproductive-age women. However, so far, there are no reliable diagnostic biomarkers for endometriosis, causing a delay in diagnosis of 6.7 ± 6.2 ye…

other 2023
Reproductive biomedicine online ·doi:10.1016/j.rbmo.2023.06.004

RESEARCH QUESTION: What is the effect of tubal endometriosis on tubal epithelial ultrastructure and is there a differential expression of exosomal microRNAs (miRNAs) in tubal fluid which may affect tubal infertility? DESIGN: Human fallopia…

article 2018
Drug design, development and therapy ·doi:10.2147/dddt.s162541

Purpose: Adenomyosis has a negative impact on female fertility. GnRH agonist treatment can improve pregnancy outcomes in women with adenomyosis. However, the impact of GnRH agonist upon endometrium receptivity of patients with adenomyosis r…

article 2015

Objective To analyze the effect of single nucleotide polymorphism(SNP)of SCN9 Agene for the patients with laparoscopic gynecologic operation.Methods A total of 200 patients with laparoscopic gynecologic operation were divided into ropivacai…

article 2009

To study the changes of tumor necrosis factor(TNF)in peritoneal fluid and serum of patients with endometriosis.TNF in peritoneal fluid and serum of 39 pa-tients with endometriosis and 16 control cases were detected by enzyme linked immunoso…

article 2007
Reproduction (Cambridge, England) ·doi:10.1530/rep-07-0104

Endometriosis, one of the most frequent diseases in gynecology, is a benign but invasive and metastatic disease. The altered expression of E-cadherin may play an important role in developing endometriosis. In this paper, we discuss the asso…

article 2006

Objective: To study the clinical effect on treating dysfunctional uterine bleeding (DUB) in perimenopausal period by using Mifepristone after diagnositic curettage. Methods: 32 cases of DUB were treated with oral Mifepristone 10mg every day…

other 2006
Molecular human reproduction ·doi:10.1093/molehr/gal002

Matrix metalloproteinases (MMPs) may contribute to the development of endometriosis. The aim of this study was to assess the effects of the polymorphisms in the promoters of MMP-7 (181A/G) and MMP-9 (1562C/T) on the risk of occurrence of en…

article 2005
Molecular human reproduction ·doi:10.1093/molehr/gah177

Matrix metalloproteinases (MMPs) may contribute to the development of endometriosis. Genetic variations in several MMP promoters may influence the transcription and expression of MMPs. The purpose of the present study was to assess how gene…