Tracie R Baker — Endo Lab

lab-animal 2025

Multi- and Transgenerational Histological and Transcriptomic Outcomes of Developmental TCDD Exposure in Zebrafish (Danio rerio) Ovary

International journal of molecular sciences ·doi:10.3390/ijms26146839

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) exposure has long been associated with reproductive dysfunction in males and females even at miniscule levels, which can persist across generations. Given the continued industrial use and detection…

meta-analysis 2024

Environmental Exposure to Per- and Polyfluorylalkyl Substances (PFASs) and Reproductive Outcomes in the General Population: A Systematic Review of Epidemiological Studies

International journal of environmental research and public health ·doi:10.3390/ijerph21121615

This Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) systematic review synthesized effects of background levels of per- and polyfluorylalkyl substance (PFAS) levels on reproductive health outcomes in the general …

lab-animal 2020

TCDD-induced multi- and transgenerational changes in the methylome of male zebrafish gonads

Environmental epigenetics ·doi:10.1093/eep/dvaa010

The legacy endocrine disrupting chemical and aryl hydrocarbon receptor agonist, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), is produced as a byproduct of industrial processes and causes adverse health effects ranging from skin irritation to…

lab-animal 2014

Using zebrafish as a model system for studying the transgenerational effects of dioxin

Toxicological sciences : an official journal of the Society of Toxicology ·doi:10.1093/toxsci/kfu006

2,3,7,8 Tetrachlorodibenzo-p-dioxin (TCDD) has been associated with many disease states in humans. A rising concern is that exposure early in life can lead to adult toxicity and toxicity in subsequent generations. Juvenile zebrafish exposed…