Benqiang Rao

No ORCID on file · 3 papers in corpus
lab-animal 2013
A recombinant adenovirus vector encoding the light chain of human coagulation factor VII and IgG1 Fc fragment to targeting tissue factor for colorectal cancer immunotherapy in the mouse model
Journal of cancer research and clinical oncology ·doi:10.1007/s00432-013-1417-1

PURPOSE: Over expression of tissue factor (TF) occurs in more than 50 % of colorectal cancer (CRC). Therefore, TF represents an attractive target antigen for immunotherapy in CRC. METHODS: Here, we assessed the safety and efficacy of a rec…

lab-animal 2011
Selective and effective killing of angiogenic vascular endothelial cells and cancer cells by targeting tissue factor using a factor VII-targeted photodynamic therapy for breast cancer
Breast Cancer Research and Treatment ·doi:10.1007/s10549-010-0957-1

The cell surface receptor tissue factor (TF) is regarded as a common but specific target on angiogenic tumor vascular endothelial cells (VECs) and tumor cells in many types of cancer including breast cancer. The purpose of this study is to …

lab-animal 2010
Targeting tissue factor on tumour cells and angiogenic vascular endothelial cells by factor VII-targeted verteporfin photodynamic therapy for breast cancer in vitro and in vivo in mice
BMC cancer ·doi:10.1186/1471-2407-10-235

BACKGROUND: The objective of this study was to develop a ligand-targeted photodynamic therapy (tPDT) by conjugating factor VII (fVII) protein with photosensitiser verteporfin in order to overcome the poor selectivity and enhance the effect …