Stuart S Martin

No ORCID on file · 2 papers in corpus

lab-animal 2022

Microtentacle Formation in Ovarian Carcinoma

Cancers ·doi:10.3390/cancers14030800

BACKGROUND: The development of chemoresistance to paclitaxel and carboplatin represents a major therapeutic challenge in ovarian cancer, a disease frequently characterized by malignant ascites and extrapelvic metastasis. Microtentacles (McT…

lab-animal 2020

Inactivation of Arid1a in the endometrium is associated with endometrioid tumorigenesis through transcriptional reprogramming

Nature communications ·doi:10.1038/s41467-020-16416-0

Somatic inactivating mutations of ARID1A, a SWI/SNF chromatin remodeling gene, are prevalent in human endometrium-related malignancies. To elucidate the mechanisms underlying how ARID1A deleterious mutation contributes to tumorigenesis, we …