Mathew Leonardi

OBJECTIVE: To identify a microbial signature for endometriosis for use as a diagnostic non-invasive biomarker. DESIGN: Prospective cohort pilot study. SETTING: Nepean Hospital and UNSW Microbiome Research Centre, Australia. POPULATION: S…

ABSTRACT Objective: To explore diagnostic preferences among individuals with confirmed or suspected endometriosis to inform the development of patient-centered diagnostic strategies. Design: Qualitative study using semi-structured focus gro…

INTRODUCTION: Understanding what patients prioritize when seeking care for endometriosis and chronic pelvic pain (CPP) is crucial for delivering personalized, responsive care. However, patient-defined goals remain poorly characterized acros…

OBJECTIVE: Adhesions between the uterus, bladder and anterior abdominal wall are associated with clinical sequelae, including chronic pelvic pain and dyspareunia, and can also yield complications during surgery. The transvaginal sonographic…

Abstract BACKGROUND Patients with endometriosis experience chronic, inflammatory symptoms including severe pelvic pain and infertility, caused by endometrial-like tissue growth outside the uterus. Endometriosis remains poorly understood, la…

BACKGROUND: Endometriosis is prevalent in approximately 6-10% of all women of reproductive age and is associated with pelvic pain, heavy menstrual bleeding, infertility, and pain during intercourse. Despite reporting symptoms, women wait ar…

INTRODUCTION: Endometriosis is a chronic inflammatory condition that affects around 1 in 7 women of reproductive age. Current medical treatments tend to be sub-optimal to manage the range of symptoms, with low levels of patient satisfaction…

OBJECTIVES: Endometriosis ultrasound is an accurate, cost-effective, and non-invasive diagnostic tool that can help improve the diagnostic delay that patients with endometriosis experience. As an emerging diagnostic method, the perspectives…

Endometriosis is a chronic condition where tissue resembling the uterine lining grows elsewhere in the pelvis, often causing pain, infertility, and inflammation. For decades, textbooks and research papers have described the rectovaginal sep…

• High prevalence of severe dysmenorrhea in patients with PCOM. • Heavy menstrual flow strongly predicts severe dysmenorrhea. • Gravidity appears protective against severe menstrual pain. • PCOM identified in nearly 20% of gynecologic ultra…

Endometriosis is a serious multifocal condition that can involve various pelvic structures, with Pouch of Douglas (POD) obliteration being a significant clinical indicator for diagnosis. To circumvent the need for invasive diagnostic proced…

• Diagnostic Challenge: Ovarian endometriomas have a characteristic ultrasound appearance but can be mimicked by various ovarian and non-ovarian pathologies. • Intraoperative Ultrasound Findings: A new cystic lesion with a ‘ground glass’ ap…

OBJECTIVE: Vaginal endometriosis occurs in 3.5% to 14.5% of patients with endometriosis [1-3]. Complete resection is crucial, as unnecessary colpotomy may increase the risk of rectovaginal fistula [4], and incomplete resection may leave res…

STUDY QUESTION: What is the relationship between sexual function, health-related quality of life (HRQoL), and laparoscopic surgery in individuals living with endometriosis? SUMMARY ANSWER: A higher number of laparoscopic surgeries is signi…

Abstract Diagnosis of endometriosis has traditionally relied on laparoscopic surgery, which was considered the ‘gold standard’ diagnostic tool. This is not ideal as surgery carries risk, is expensive, is difficult to access, and disrupts pa…

PURPOSE: The aim of this study was to investigate the current application of artificial intelligence (AI) tools in the teaching of ultrasound skills as they pertain to gynaecological ultrasound. METHODS: A scoping review was performed. Eig…

Endometriosis is a prevalent gynecological disease, leading to chronic pain and inflammation, affecting 1 in 10 individuals presumed female at birth. The diagnostic journey is often arduous, marked by neglect of the right diagnosis and prol…

Objective To identify a diagnostic microbial signature for endometriosis. Design Prospective cohort study Setting Nepean Hospital and UNSW Microbiome Research Centre, St George Hospital, Australia Population 64 age- and sex-matched subjects…

In March 2022 Australian Medicare Benefits Schedule updated gynecological item numbers relating to endometriosis surgery. Specific item numbers include 35637, 35631 and 35632 (a division of 35638) and 35641 (14). Each item number correlates…