Mathew Leonardi

INTRODUCTION: Endometriosis is a heterogeneous pain condition with variable symptom expression. Abuse history has been associated with amplified pain, gastrointestinal symptoms, and central sensitization in varying populations; however, whe…

OBJECTIVE: To (1) determine how application of the updated international definition of deep endometriosis (DE) alters apparent disease prevalence across pelvic sites, and (2) characterize the distribution of endometriosis phenotypes, includ…

Background Rapid advances in transvaginal ultrasound techniques to detect endometriosis (eTVUS) require navigation of a steep learning curve. Artificial intelligence (AI) is playing an ever-increasing role in ultrasound and holds potential …

OBJECTIVE: To investigate, using transvaginal ultrasound imaging, the overlap between polycystic ovarian morphology (PCOM) and endometriosis, and to explore demographic and clinical factors associated with their coexistence across endometri…

Knowledge pertaining to the interplay between body image, body compassion, and endometriosis-related symptoms is limited. The current study aimed to elucidate the relationships between body compassion, body image, and endometriosis-related …

Objective To characterize patterns of glucagon-like peptide-1 receptor agonist (GLP-1RA) use and their perceived effects on endometriosis-related symptoms, quality of life, treatment burden, and symptom recurrence following discontinuation.…

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In this study, we evaluate a locally-deployed large-language model (LLM) to convert unstructured endometriosis transvaginal ultrasound (eTVUS) scan reports into structured data for imaging informatics workflows. Across 49 eTVUS reports, we …

Endometriosis affects 1 in 10 women globally. We aimed to determine health provider involvement and preferred methods of obtaining an endometriosis diagnosis across international jurisdictions. A global cross-sectional survey, distributed t…

OBJECTIVE: To provide health care professionals with an evidence-based approach to the management of endometriosis and its associated symptoms. TARGET POPULATION: Women and gender-diverse individuals affected by endometriosis. BENEFITS, H…

Background Chronic pelvic pain (CPP) is often described as a multisystem pain condition, yet population-level evidence on adolescent antecedents is scarce. We examined whether healthcare encounters for gynecologic or reproductive morbidity …

Endometriosis is a chronic, debilitating condition characterized by heterogenous clinical manifestations. It has a prevalence of 5-10% in women of reproductive age, and 30-50% of individuals with endometriosis are affected by infertility. T…

Abstract Adenomyosis and deep endometriosis frequently coexist and represent a major challenge in the assessment and management of infertility. Both conditions are associated with impaired uterine function, pelvic inflammation, and distorte…

OBJECTIVE: Canadians with endometriosis experience significant delays in access to care within our national health care system. This study aims to discern the factors leading individuals with suspected and/or confirmed endometriosis to seek…

Endometriosis is a chronic, inflammatory gynecologic disease affecting approximately 10% of individuals assigned female at birth worldwide and is associated with substantial morbidity, reduced quality of life, and significant diagnostic del…

Endometriosis is a chronic, inflammatory gynecologic disease affecting approximately 10% of individuals assigned female at birth worldwide and is associated with substantial morbidity, reduced quality of life, and significant diagnostic del…

OBJECTIVE: To explore diagnostic preferences among individuals with confirmed or suspected endometriosis to inform the development of patient-centred diagnostic strategies. DESIGN: Qualitative study using semi-structured focus group discus…