Chun-Yan Wei

No ORCID on file · 8 papers in corpus · active 2014-2025

Study types

  • article 5
  • other 3

Condition tags

  • endometriosis 8
  • mesh:D004715 7
other 2025
Creatine promotes endometriosis progression by inducing M2 polarization of peritoneal macrophages
Reproduction (Cambridge, England) ·doi:10.1530/REP-24-0278

IN BRIEF: Endometriosis (EM) is a chronic inflammatory disease with unclear pathogenesis, in which peritoneal macrophages play a pivotal role. This study demonstrates that creatine (CR) induces M2 polarization of peritoneal macrophages, pro…

other 2023
Heme induced progesterone-resistant profiling and promotion of endometriosis in vitro and in vivo
Biochimica et biophysica acta. Molecular basis of disease ·doi:10.1016/j.bbadis.2023.166761

Endometriosis is an estrogen-dependent, progesterone-resistant gynecological disease with an unknown pathogenesis. Compared to women without endometriosis, women with endometriosis have a remarkably high heme level in the peritoneal fluid. …

article 2019
Elevated heme impairs macrophage phagocytosis in endometriosis
Reproduction (Cambridge, England) ·doi:10.1530/rep-19-0028

Endometriosis (EMS) is a chronic inflammatory disease characterized by the presence of extrauterine endometrial tissues. It has been previously reported that the refluxed blood containing viable endometrial tissues and the defective elimina…

other 2018
Suppression of autophagy and HCK signaling promotes PTGS2high FCGR3- NK cell differentiation triggered by ectopic endometrial stromal cells
Autophagy ·doi:10.1080/15548627.2018.1476809

UNLABELLED: Impaired NK cell cytotoxic activity contributes to the local dysfunctional immune environment in endometriosis (EMS), which is an estrogen-dependent gynecological disease that affects the function of ectopic endometrial tissue c…

article 2017
IL-27 triggers IL-10 production in Th17 cells via a c-Maf/RORγt/Blimp-1 signal to promote the progression of endometriosis
Cell death & disease ·doi:10.1038/cddis.2017.95

Abstract Endometriosis is an estrogen-dependent inflammatory disease. The anti-inflammatory cytokine IL-10 is also increased in endometriosis. IL-10 production by Th17 cells is critical for limiting autoimmunity and inflammatory responses. …

article 2016
IL15 promotes growth and invasion of endometrial stromal cells and inhibits killing activity of NK cells in endometriosis
Reproduction (Cambridge, England) ·doi:10.1530/rep-16-0089

Endometriosis (EMS) is associated with an abnormal immune response to endometrial cells, which can facilitate the implantation and proliferation of ectopic endometrial tissues. It has been reported that human endometrial stromal cells (ESCs…

article 2016
Macrophages promote the growth and invasion of endometrial stromal cells by downregulating IL-24 in endometriosis
Reproduction (Cambridge, England) ·doi:10.1530/rep-16-0278

Macrophages play an important role in the origin and development of endometriosis. Estrogen promoted the growth of decidual stromal cells (DSCs) by downregulating the level of interleukin (IL)-24. The aim of this study was to clarify the ro…

article 2014
Indoleamine 2,3-dioxygenase-1 (IDO1) in human endometrial stromal cells induces macrophage tolerance through interleukin-33 in the progression of endometriosis.
International journal of clinical and experimental pathology

In the peritoneal fluid, macrophages and their secretory cytokines are essential for endometriosis, but the factors that favor their involvement in the endometriosis-associated inflammatory response are still elusive. Given the anomalous ex…