Rajeshwar R Tekmal

No ORCID on file · 34 papers in corpus · active 1994-2024

Study types

  • article 34

Condition tags

  • endometriosis 10
  • mesh:D004715 9
  • endometrioma 1
article 2024
HYALURONIC ACID SYSTEM IN RHESUS MONKEYS AS A MODEL FOR STUDYING THE PATHOGENESIS OF EARLY ENDOMETRIOTIC LESIONS
·doi:10.1016/j.fertnstert.2024.07.120
article 2023
EFFECTS OF THE ERβ AGONIST LY ON ATTACHMENT AND INVASION OF ENDOMETRIAL CELLS
·doi:10.1016/j.fertnstert.2023.08.420
article 2021
HYALURONIC ACID PATHWAY EXPRESSION IN ESTROGEN-PROGESTERONE TREATMENT AND PROGESTERONE ONLY TREATMENT OF ENDOMETRIOSIS
·doi:10.1016/j.fertnstert.2021.07.569
article 2021
HYALURONIC ACID PATHWAY EXPRESSION IN PAIRED EUTOPIC ENDOMETRIAL AND ENDOMETRIOMA CELLS
·doi:10.1016/j.fertnstert.2021.07.555
article 2020
CD44 variant 6 is involved in the attachment and invasion of endometrial cells to peritoneum
F&S science ·doi:10.1016/j.xfss.2020.08.002

Objective To study the effects of CD44 standard (CD44s), CD44v3, and CD44v6 overexpression (OE) on immortalized human endometrial epithelial (iEECs) and stroma cells (human endometrial stromal cells [hESCs]) using in vitro assays and a nude…

article 2020
EFFECT OF IL-6 AND TNF ALPHA ON INVASION OF EPITHELIAL AND STROMAL ENDOMETRIAL CELLS IN AN IN VITRO MODEL OF HUMAN PERITONEUM
·doi:10.1016/j.fertnstert.2020.08.1064
article 2020
Inhibition of Hyaluronic Acid Synthesis Decreases Endometrial Cell Attachment, Migration, and Invasion
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1007/s43032-019-00100-w
article 2019
3332 Overexpression of CD44 is involved in the development of the early endometriotic lesion in a xenograft model
·doi:10.1017/cts.2019.255

OBJECTIVES/SPECIFIC AIMS: Previously, we showed decreased development of endometriotic lesions in CD44 knockout mice compared to control.(1) CD44 has 10 different variants and a standard form. Menstrual endometrial cells (MECs) from women w…

article 2018
Endometrial cell invasion is decreased with inhibition of hyaluronic acid synthesis
·doi:10.1016/j.fertnstert.2018.07.1094
article 2018
Knockdown of cd44 decreases attachment but not invasion of endometrial epithelial cells
·doi:10.1016/j.fertnstert.2018.07.1089
article 2018
Overexpression of CD44 is involved in the development of the early endometriotic lesion
·doi:10.1016/j.fertnstert.2018.07.1090
article 2018
The Hyaluronic Acid System is Intact in Menstrual Endometrial Cells in Women With and Without Endometriosis
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719118766257
article 2017
2114
Journal of clinical and translational science ·doi:10.1017/cts.2017.203

OBJECTIVES/SPECIFIC AIMS: To further elucidate the role of estrogen receptor β (ER-β) in the early endometriotic lesion attachment. METHODS/STUDY POPULATION: EECs were immortalized using a telomerase vector. Immortalized cells and parental …

article 2017
The role of estrogen receptor beta in development of the early endometriotic lesion
·doi:10.1016/j.fertnstert.2017.07.589
article 2015
Impaired Development of Early Endometriotic Lesions in CD44 Knockout Mice
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719115594022
article 2014
Endometrial epithelial cell expression of estrogen receptor isoforms alpha and beta alters attachment to peritoneal mesothelial cells
·doi:10.1016/j.fertnstert.2014.07.988
article 2013
Ovarian steroid alter endometrial epithelial cell attachment to peritoneal mesothelial cells
·doi:10.1016/j.fertnstert.2013.07.773
article 2012
Increased expression of macrophage colony–stimulating factor and its receptor in patients with endometriosis
Fertility and sterility ·doi:10.1016/j.fertnstert.2012.02.007
article 2012
Raf-1, a Potential Therapeutic Target, Mediates Early Steps in Endometriosis Lesion Development by Endometrial Epithelial and Stromal Cells
Endocrinology ·doi:10.1210/en.2011-1879

Endometriosis is a hormone-sensitive gynecological disorder characterized by the benign growth of endometrial-like tissue in the pelvic cavity. Endometriotic lesions composed of endometrial stromal cells (ESC) and glandular epithelial cells…

article 2011
Colony-stimulating factor-1 exerts direct effects on the proliferation and invasiveness of endometrial epithelial cells
Fertility and sterility ·doi:10.1016/j.fertnstert.2011.03.026
article 2010
Imatinib decreases endometrial stromal cell transmesothial migration and proliferation in the extracellular matrix of modeled peritoneum
Fertility and sterility ·doi:10.1016/j.fertnstert.2010.04.018
article 2009
Induction of endometrial epithelial cell invasion and c-fms expression by transforming growth factor beta
Molecular human reproduction ·doi:10.1093/molehr/gap043

Transforming growth factor beta 1 (TGF-beta1) levels are increased in the peritoneal fluid of endometriosis patients, and endometrial cells express TGF-beta signaling components; however, little is known regarding the role of TGF-beta in en…

article 2009
Menstrual endometrial cells from women with endometriosis demonstrate increased adherence to peritoneal cells and increased expression of CD44 splice variants
Fertility and sterility ·doi:10.1016/j.fertnstert.2008.12.012
article 2008
A potential role for colony-stimulating factor 1 in the genesis of the early endometriotic lesion
Fertility and sterility ·doi:10.1016/j.fertnstert.2008.09.050
article 2008
Imatanib alters expression of endometrial stromal cell signaling genes involved in cell proliferation and metastasis
·doi:10.1016/j.fertnstert.2008.07.244