Zhao P

INTRODUCTION: Endometriosis, a chronic gynecological disorder, significantly impacts fertility and quality of life. Identifying effective therapeutic targets is critical for their management. OBJECTIVES: The objective of this study was to …

BACKGROUND: Repeated implantation failure (RIF) is a key challenge in assisted reproductive technology (ART), and its mechanism is closely related to Endometrial receptivity (ER). Although the effects of some Endometrial receptivity paramet…

OBJECTIVE: This study aims to assess the effects of intrauterine infusion of human umbilical cord blood mononuclear cells (HUCBMCs) on reproductive outcomes in patients with thin endometrium undergoing frozen embryo transfer (FET). DESIGN:…

BACKGROUND & AIMS: Pancreatitis is influenced by environmental and genetic factors. Genome-wide association studies identified polymorphisms at the X-linked CLDN2 locus as risk factors for chronic pancreatitis. CLDN2 encodes claudin-2 (CLDN…

OBJECTIVE: The ovary, as an important reproductive organ, tightly regulates the litter size of rabbits through its complex network of genes. This study aims to identify candidate genes related to litter size in rabbits through RNA sequencin…

BACKGROUND: Endometriosis is a chronic gynecological disorder characterized by the presence of endometrial-like tissue outside the uterine cavity, causing chronic pain and infertility. Hypoxia plays a significant role in the progression of …

OBJECTIVE: The association between anti-Müllerian hormone (AMH) levels and embryonic aneuploidy rates was investigated by analyzing clinical and embryo laboratory data from patients with preimplantation genetic testing for aneuploidy (PGT-A…

BACKGROUND: The clinical prognostic factors for ovarian clear cell carcinoma (OCCC) are limited, and we aim to construct a model to predict the survival of OCCC patients. METHODS: Data were extracted from the SEER database for patients dia…

BACKGROUND: Gonadotropin-releasing hormone (GnRH) antagonist and long-acting GnRH agonist regimens are commonly employed for ovarian stimulation in women undergoing in-vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI), but t…

BACKGROUND: Intrauterine adhesions (IUAs) is a gynecological condition with a poor therapeutic prognosis, that severely threatens the fertility and the reproductive physiology and psychological health of women. Our previous research on the …

BACKGROUND: Immunotherapy has emerged as a novel strategy for cancer treatment following surgery, radiotherapy, and chemotherapy. Immune checkpoint blockade and Chimeric antigen receptor (CAR)-T cell therapies have been successful in clinic…

Endometriosis seriously affects 6-10 % of reproductive women globally and poses significant clinical challenges. The process of ectopic endometrial cell colonization shares similarities with cancer, and a dysfunctional immune microenvironme…

ABSTRACT Pancreatitis is an inflammatory disease of the pancreas that can arise due to various factors, including environmental risks such as diet, alcohol, and smoking, as well as genetic predispositions. In some cases, pancreatitis may p…

Ovarian cancer (OC) is one of the most lethal malignancies of the female reproductive system. OC patients are usually diagnosed at advanced stages due to the lack of early diagnosis. The standard treatment for OC includes a combination of d…

Cancer is currently one of the most intractable diseases causing human death. Although the prognosis of tumor patients has been improved to a certain extent through various modern treatment methods, multidrug resistance (MDR) of tumor cells…

BACKGROUND: Pulmonary tuberculosis (PTB) remains the world's deadliest infectious killer. Serum CA-125 test are useful in the diagnosis of PTB. Although studies on the relation between CA-125 and PTB have been reported, the specificity and …

Hemopexin (Hx) is a scavenger of labile heme. Herein, we present data defining the role of tumor stroma-expressed Hx in suppressing cancer progression. Labile heme and Hx levels are inversely correlated in the plasma of patients with prosta…

This retrospective study analyzed the effectiveness of neuromuscular electrical stimulation (NMES) for pain relief caused by necrosis of femoral head (NFH).Totally, 80 cases of patients with NFH were analyzed and then were assigned to a tre…

Hemangiopericytoma (HPC) and meningioma, for their morphology immunohistochemical markers similarity, were usually confused especially before surgery. This study aimed to develop a panel of biomarkers to differentiate HPC from meningioma. R…

BACKGROUND: Recent evidence from rodent ovaries has demonstrated expression of fractalkine and the existence of fractalkine receptor, and showed that there is a significant increase in steroidogenesis in response to fractalkine, yet the rol…

AIM: To study the correlation between the patterns of subcellular expression of p16 and CDK4 in colorectal epithelia in the normal-adenoma-carcinoma sequence. METHODS: Paraffin sections of 43 cases of normal colorectal epithelia and corres…