Nelson AC

ORCID: 0000-0002-4741-0010 · 3 papers in corpus
other 2026
Frontiers in systems biology ·doi:10.3389/fsysb.2026.1729027

Osteoporosis is a skeletal pathology characterized by decreased bone mass and structural deterioration resulting from an imbalance in bone metabolic processes. Estrogen deficiency in postmenopausal women leads to an increased risk of osteop…

nonrandomized-trial 2025
Clinical cancer research : an official journal of the American Association for Cancer Research ·doi:10.1158/1078-0432.ccr-25-1878

PURPOSE: To evaluate exemestane, an aromatase inhibitor, as a preventive intervention for endometrial cancer. EXPERIMENTAL DESIGN: This is a multicenter, single-arm, "window of opportunity" pilot study of exemestane (25 mg daily for 21-42 …

other 2022
Cancer research communications ·doi:10.1158/2767-9764.crc-22-0122

Targeting glutamine metabolism has emerged as a novel therapeutic strategy for several human cancers, including ovarian cancer. The primary target of this approach is the kidney isoform of glutaminase, glutaminase 1 (GLS1), a key enzyme in …